Abstract
A 9 month old female infant, who had BCG vaccination postnatally, was found to have severe combined immunodeficiency. She developed extensive disseminated skeletal osteomyelitis. Radiological studies showed numerous radiolucent lesions without reactive changes.
References
Matsaniotis N (1967) Dangers of immunization in immunologically incompetent individuals. ACTA Paediatr Scand [Supp.] 172:146
Bouton J, Mainwaring D, Smithells RW (1963) BCG dissemination in congenital hypogammaglobulinaemia. Br Med J 1: 1512
Mortensson W, Eklof O, Jorulf H (1976) Radiologic aspects of BCG osteomyelitis in infants and children. Acta Radiol Diagn 17:845
Sacrez R, Levy M, Reys P, Kirsch W, Lahlou B (1967) Dissemination de bacille tuberculeux bovin apres administration a un enfant de bans de BCG lesions cutanees osseuses et ganglionnaires multiples. Guerison. Pediatrie 22:435
Imerslund O, Jonsen T (1954) Lupus vulgaris and multiple bone lesions caused by BCG. ACTA Tub Scand 30:116
Fisher RH (1953) Multiple lesions of bone in Letterer-Siwe disease. J Bone Joint Surg 35A:445
Cederbaum SD, Niwayama G, Stiehm ER, Neerhout RC, Ammann AJ, Berman Jr W (1974) Combined immunodeficiency presenting as the Letterer-Siwe disease. J Pediatr 85:460
Condon VR, Allen RP (1961) Congenital generalized fibromatosis. Radiology 76: 444
Shopfner CE, Allan RP (1961) Lymphangioma of bone. Radiology 76:449
Yakovac WC, Baker R, Sweigert C, Hope JW (1961) Fatal disseminated osteomyelitis due to an anonymous mycobacterium. J Pediatr 59:909
Van der Hoeven LP, Ruthen FJ, van der Sar A (1958) An unusual acid-fast bacillus causing systemic disease and death in a child. Am J Clin Pathol 29:433
Bender BL, Yunis EJ (1980) Disseminated nongranulomatous mycobacterium avium osteomyelitis. Hum Pathol 11:476
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hugosson, C., Harfi, H. Disseminated BCG-osteomyelitis in congenital immunodeficiency. Pediatr Radiol 21, 384–385 (1991). https://doi.org/10.1007/BF02011498
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02011498