Abstract
A protocol based on anti-IgE induced human basophil activation was set up to allow the intra-assay calculation of basophil count significance. In 6 successive experiments, we demonstrated the normality of the basophil count distribution through a comparison of the mean values by Student's t-test. We confirm the inhibition of anti-IgE induced human basophil activation by histamine dilutions ranging from 10−10 M to 10−38 M, the most frequent inhibition observed being for 10−18, 10−20, and 10−32 M, in agreement with our previous results.
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Sainte-Laudy, J., Belon, P. Inhibition of human basophil activation by high dilutions of histamine. Agents and Actions 38, C245–C247 (1993). https://doi.org/10.1007/BF01996474
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DOI: https://doi.org/10.1007/BF01996474