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The effect of a gastric mucus barrier on the dynamic response of a pH electrode

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Summary

Hydrogen ion mobility in gastric mucus has been found to be reduced to a greater extent than that hitherto suspected, though at low pH (<4) and in buffer this mobility increases. Mucus, at an optimized pH, may therefore protect the gastric mucosa from acid digestion by providing a diffusion barrier.

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Authors and Affiliations

  1. Department of Clinical Biochemistry and Metabolic Medicine, Royal Victoria Infirmary, NE1 4LP, Newcastle upon Tyne, UK

    P. Vadgama & K. G. M. M. Alberti

Authors
  1. P. Vadgama
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  2. K. G. M. M. Alberti
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Additional information

We wish to thank Professor A. Allen for providing us with pig gastric mucus, and Dr A. K. Covington for his help and advice during the preparation of this manuscript.

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Vadgama, P., Alberti, K.G.M.M. The effect of a gastric mucus barrier on the dynamic response of a pH electrode. Experientia 39, 573–576 (1983). https://doi.org/10.1007/BF01971102

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  • DOI: https://doi.org/10.1007/BF01971102

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