Skip to main content
Log in

Spread of cobalt from a cortical epileptic lesion induced by a cobalt-gelatine implant into the frontal cortex of the rat

  • Pharmacologica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

The spread of cobalt ions from cobalt induced epileptic foci in rats has been investigated. Atomic absorption spectrophotometry and heavy-metal histochemistry reveal cobalt ions spread very widely from the focus. Biochemical and physiological consequences for this model of epilepsy are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. L. M. Kopeloff, S. E. Barrera andN. Kopeloff, Am. J. Psychiat.98, 881 (1942).

    Article  CAS  Google Scholar 

  2. P. C. Emson, inBiochemistry and Neurology (Eds.H. F. Bradford andC. D. Marsden: Academic Press, New York 1976), p. 163.

    Google Scholar 

  3. R. C. Dow, J. K. McQueen andH. R. A. Townsend, Epilepsia13, 459 (1972).

    Article  CAS  PubMed  Google Scholar 

  4. R. S. Dow, A. Fernandez-Guardiola andE. Manni, Electroenceph. clin. Neurophysiol.14, 399 (1962).

    Article  CAS  PubMed  Google Scholar 

  5. R. M. Pitman, C. D. Tweedle andM. J. Cohen, Science176, 412 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. G. V. Goddard, Nature, Lond.214, 1020 (1967).

    Article  CAS  PubMed  Google Scholar 

  7. J. Fischer, J. Holubar andV. Malik, Physiologia bohemoslov.16, 272 (1967).

    CAS  Google Scholar 

  8. F. Timm, Dt. Z. ges. gericht. Med.46, 706 (1958).

    CAS  Google Scholar 

  9. F.-M. S. Haug, Z. Anat. EntwGesch.145, 1 (1974).

    Article  CAS  Google Scholar 

  10. P. C. Emson andM. H. Joseph, Brain REs.93, 91 (1975).

    Article  CAS  PubMed  Google Scholar 

  11. P. R. Clayton andP. C. Emson, Biochem. Soc. Trans.3, 261 (1975).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Clayton, P.R., Emson, P.C. Spread of cobalt from a cortical epileptic lesion induced by a cobalt-gelatine implant into the frontal cortex of the rat. Experientia 32, 1303–1305 (1976). https://doi.org/10.1007/BF01953106

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01953106

Keywords

Navigation