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The lack of an effect of cholinergic agonists on anterior pituitary prolactin production in vitro

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Summary

The addition of dopamine to anterior pituitary incubations resulted in a marked decrease (88% for3H prolactin and 69% for RIA prolactin) in prolactin release. Incubation with the cholinergic agonists carbacol, arecoline and nicotine resulted in no significant change in prolactin secretion.

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Literatur

  1. M. G. Subramanian and R. R. Gala, Endocrinology98, 842 (1976).

    Article  CAS  PubMed  Google Scholar 

  2. D. M. Lawson and R. R. Gala, Endocrinology96, 313 (1975).

    Article  CAS  PubMed  Google Scholar 

  3. W. Vale, C. Rivier, M. Brown, L. Chan, N. Ling and J. Rivier, in: Hypothalamus and Endocrine Functions, p. 397. Ed. F. Labrie, J. Meites, and G. Pelletier. Plenum Press, New York 1976.

    Chapter  Google Scholar 

  4. R. M. MacLeod and J. E. Lehmeyer, Endocrinology94, 1077 (1974).

    Article  CAS  PubMed  Google Scholar 

  5. E. Y. H. Kuo and R. R. Gala, Biochim. biophys. Acta264, 462 (1972).

    Article  CAS  PubMed  Google Scholar 

  6. R. M. MacLeod and A. Abad, Endocrinology83, 799 (1968).

    Article  CAS  PubMed  Google Scholar 

  7. M. G. Subramanian and R. R. Gala, Proc. Soc. exp. Biol. Med.155, 353 (1977).

    Article  CAS  PubMed  Google Scholar 

  8. L. Grandison and J. Meites, Endocrinology99, 775 (1976).

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Physiology, Wayne State University School of Medicine, 48201, Detroit, Michigan, USA

    M. D. Campbell, S. Jaques Jr & R. R. Gala

Authors
  1. M. D. Campbell
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  2. S. Jaques Jr
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  3. R. R. Gala
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Additional information

Supported in part by NSF Research grant No. BMS 74-17332.

The authors appreciate receiving as a gift from the National Institute of Arthritis, Metabolic and Digestive Diseases, the rat prolactin used for iodination (RP-I2) and standards (RP-1).

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Campbell, M.D., Jaques, S. & Gala, R.R. The lack of an effect of cholinergic agonists on anterior pituitary prolactin production in vitro. Experientia 34, 1522–1523 (1978). https://doi.org/10.1007/BF01932389

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  • DOI: https://doi.org/10.1007/BF01932389

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