Summary
Plasma amine oxidase activity increased from 23.4 nmol/ml/h during pregnancy to 49.5 nmol/ml/h during an extended post partum period in 10 rhesus monkeys. Comparison with non-pregnant control monkeys sampled at similar times indicated that the significant differences were in the extended post partum period.
Similar content being viewed by others
References
M. L. C. Hare, Biochem. J.22, 986 (1928).
I. J. Kopin, Pharmac. Rev.16, 179 (1964).
F. Costa andP. Greengard,Advances in Biochemical Psychopharmacology (Raven Press, New York 1972), vol. 5.
N. Weiner andR. Bjur, inAdvances in, Biochemical Psychopharmacology, (Eds.F. Costa andP. Greengard; Raven Press, New York 1972), vol. 5, p. 409.
D. L. Murphy, C. H. Donnelly, andM. Buchsbaum, in preparation (1976).
J. P. Johnston, Biochem. Pharmac.17, 1285 (1968).
N. H. Neff andC. Goridis, inAdvances in Biochemical Psychopharmacology (Eds.F. Costa andP. Greengard; Raven Press, New York 1972), vol. 5, p. 307.
C. H. Donnelly andD. L. Murphy, in preparation (1976).
C. M. McEwen, Jr., J. biol. Chem.240, 2003 (1965).
C. M. Mcewen, Jr., inAdvances in Biochemical Psychopharmacology (Eds.F. Costa andP. Greengard; Raven Press, New York 1972), vol. 5, p. 151.
N. Tryding, S. E. Nilsson, G. Tifvesson, B. Berg, S. Carlstrom, B. Elmfors, andJ. E. Nilsson, Scand. J. clin. Lab. Invest.23, 79 (1969).
N. J. Gilmore, D. S. Robinson, A. Nies, D. Sylvester andC. J. Ravaris, J. Psychosom. Res.15, 215 (1971).
M. Briggs andM. Briggs, J. Reprod. Fert.29, 447 (1972).
E. A. Zeller, B. H. Babu, M. J. Cavanaugh andG. H. Stanich, Pharmac. Res. Commun.1, 20 (1969).
D. L. Murphy andC. H. Donnelly, inNeuropsychopharmacology of Monoamines and their Regulatory Enzymes (Raven Press, New York 1974), p. 71.
E. L. Klaiber, Y. Kobayashi, D. M. Broverman andF. Hall, J. clin. Endocrinology33, 630 (1971).
R. H. Belmaker, D. L. Murphy, R. J. Wyatt andD. L. Loriaux, Arch. gen. Psych.31, 553 (1974).
D. E. Redmond, Jr., D. L. Murphy, J. Baulu, M. G. Zeigler andC. R. Lake, Psychosom. Med.37, 417 (1975).
D. S. Robinson, W. Lovenberg, H. Keiser andJ. Sjoerdsma, Biochem. Pharmac.17, 109 (1968).
B. J. Winer,Statistical Principles in Experimental Design, 2nd edn. McGraw Hill, New York 1962), p. 514.
A. J. Zolovick, R. Pearse, K. W. Boehlke andB. E. Eleftheriou, Science154, 649 (1966).
G. C. S. Collins, M. Sandler, E. D. Williams, andM. B. H. Youdim, Nature, Lond.225, 817 (1970).
H. Thoms, inClassical Contributions to Obstetrics and Gynecology (Charles C. Thomas, Springfield 1935).
B. C. Stevens, Soc. Sci. Med.5, 527 (1971).
C. Protheroe, Br. J. Psychiat.115, 9 (1969).
G. C. Rosenwald andM. W. Stonehill, Psychosom, Med.34, 129 (1972).
K. Dalton, Proc. R. Soc. Med.64, 1249 (1971).
W. A. Brown andP. Shereshefsky, Psychiatry34, 139 (1972).
A. Nies, D. S. Robinson, C. L. Ravaris andJ. M. Davis, Psychosom. Med.33, 470 (1971).
D. L. Murphy andR. Weiss, Am. J. Psychiatr.128, 1351 (1972).
J. Bockar, R. H. Roth andG. Heninger, Life Sci.15, 2109 (1974).
D. L. Murphy andR. J. Wyatt, Nature, Lond.238, 225 (1972).
R. J. Wyatt, D. L. Murphy, R. Belmaker, S. Cohen, C. H. Donnelly andW. Pollin, Science179, 916 (1973).
A. Nies, D. S. Robinson, L. S. Harris andK. R. Lamborn, Adv. Biochem. Psychopharmac.12, 59 (1974).
H. Meltzer andS. M. Stahl, Res. Commun. Chem. Path. Pharmac.7, 419 (1974).
Author information
Authors and Affiliations
Additional information
We thank Dr.C. H. Conaway and Dr.J. D. Loy of the Caribbean Primate Research Center andJ. G. Vandenbergh andW. Post of the North Carolina Department of Mental Health for the use of their facilities and animals. We also acknowledge the technical assistance ofC. H. Donnelly andMs. Suzanne Baulu. This work was supported by a grant from Dr.H. C. Robinson, Jr., through Yale University Medical School and by NIH Contract No. 71-2003.
Rights and permissions
About this article
Cite this article
Redmond, D.E., Baulu, J. & Murphy, D.L. Pre- and post-partum plasma amine oxidase differences in the rhesus monkey (Macaca mulatta). Experientia 32, 1213–1215 (1976). https://doi.org/10.1007/BF01927632
Issue Date:
DOI: https://doi.org/10.1007/BF01927632