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Cerebrospinal fluid 5-hydroxyindoleacetic acid level in migrainous patients during spontaneous attacks, during headache-free periods and following treatment withl-tryptophan

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Riassunto

La concentrazione di acido 5-idrossindolacetico nel liquor lombare di pazienti emicranici diminuisce lievemente e non significativamente durante l'attacco, mentre, in periodo intercritico, non è diversa da quella osservata nei soggetti normali. La somministrazione dil-triptofano porta costantemente ad un incremento dei livelli di acido 5-idrossindolacetico nel liquor lombare di soggetti emicranici, oltre ad esercitare un'azione preventiva degli accessi di cefalea.

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Authors and Affiliations

  1. Clinica delle Malattie Nervose e Mentali dell' Università, Via Palestro 3, I-27100, Pavia, Italy

    M. Poloni, G. Nappi, A. Arrigo & F. Savoldi

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  1. M. Poloni
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  2. G. Nappi
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  3. A. Arrigo
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  4. F. Savoldi
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Poloni, M., Nappi, G., Arrigo, A. et al. Cerebrospinal fluid 5-hydroxyindoleacetic acid level in migrainous patients during spontaneous attacks, during headache-free periods and following treatment withl-tryptophan. Experientia 30, 640–641 (1974). https://doi.org/10.1007/BF01921518

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