Summary
Using a rat cDNA probe encoding for the C-terminal textension of the large neurofilament subunit (NF-H), we have assigned, by in situ hybridization, the human NF-H gene to the q121–q131 region of chromosome 22. This localization may have implications in neurological diseases such as meningioma where a recessive locus involved in oncogenesis is located within this region.
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Mattei, M.G., Dautigny, A., Pham-Dinh, D. et al. The gene encoding the large human neurofilament subunit (NF-H) maps to the q121–q131 region on human chromosome 22. Hum Genet 80, 293–295 (1988). https://doi.org/10.1007/BF01790100
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DOI: https://doi.org/10.1007/BF01790100