Abstract
We report on a patient suffering from multiple myeloma, for whom allogeneic bone marrow transplantation was planned. Donor workup revealed monoclonal gammopathy of unknown significance. We discuss this finding and stress the importance of performing complete donor examinations.
Similar content being viewed by others
References
Alexanian R, Haut A, Khan AU, Lane M, McKelvey E, Migliore P, Stuckey W, Wilson H (1969) Treatment for multiple myeloma: combination chemotherapy with different melphalan dose regimens. JAMA 208: 1680–1685
Bersagel DE, Bailey AJ, Langley GR, McDonald R, White D, Miller A (1979) The chemotherapy of plasma cell myeloma and the incidence of acute leukemia. N Engl J Med 301: 743–748
Buckner CD, Clift RA, Sanders JE, Stewart P, Bensinger WI, Doney KC, Sullivan KM, Witherspoon RP, Deeg HJ, Appelbaum FR, Storb R, Thomas ED (1984) Marrow harvesting from normal donors. Blood 64: 630–634
Gahrton G, Tura S, Ljungman P, Belanger C, Brandt L, Cavo M, Facon T, Granena A, Gore M, Gratwohl A, Löwenberg B, Nikoskelainen J, Reiffers JJ, Samson D, Verdonck L, Volin L (1991) Allogeneic bone marrow transplantation in multiple myeloma. N Engl J Med 325: 1267–1273
Gregory WM, Richards MA, Malpas JS (1992) Combination Chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: an overview of published trials. J Clin Oncol 10: 334–342
Jagannath S, Jagannath S, Barlogie B (1992) Autologous bone marrow transplantation for multiple myeloma. Hematol Oncol Clin North Am 6: 437–449
Mandelli F, Avvisati G, Amadori S, Boccadori M, Gernone A, Lauta V, Marmont F, Petrucci M, Tribalto M, Vegna M, Damacco F, Pileri A (1990) Maintenance treatment with recombinant interferon α-2b in patients with multiple myeloma responding to conventional induction chemotherapy. N Engl J Med 322: 1430–1434
Nietwieser DW, Appelbaum FR, Gastl G, Gersdorf E, Meister B, Geissler D, Tratkiewicz JA, Thaler J, Huber C (1990) Inadvertent transmission of a donor's acute myeloid leukemia in bone marrow transplantation for chronic myelocytic leukemia. N Engl J Med 322: 1794–1796
Oken MM, Kyle RA, Greipp PR, Kay NE, Tsiatis A, Conell MJ (1990) Chemotherapy plus interferon (rIFN-α 2) in the treatment of multiple myeloma. Proc Am Aoc Clin Oncol 9: 288 (abstract 1116)
Osgood EE (1960) The survival time of patients with plasmocytic myeloma. Cancer Chemother Rep: 1–10
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Peters, S.O., Stockschläder, M., Zeller, W. et al. Monoclonal gammopathy of unknown significance in a bone marrow donor. Ann Hematol 66, 93–95 (1993). https://doi.org/10.1007/BF01695891
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01695891