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Transcription from the pseudorabies virus genome during latent infection

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Summary

Trigeminal ganglia from swine latently infected with pseudorabies virus (PRV) were examined for the presence of PRV nucleic acids by in situ hybridization. Both viral DNA and RNA were detectable in latently infected neurons, indicating that the PRV genome is transcriptionally active during the latent phase of infection.

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Author notes

  1. D. L. Rock & F. A. Osorio

    Present address: Department of Veterinary Science, University of Nebraska-Lincoln, NE 68583-0905, Lincoln, USA

Authors and Affiliations

  1. Veterinary Medical Research Institute and Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA

    D. L. Rock, W. A. Hagemoser, F. A. Osorio & H. A. McAllister

Authors
  1. D. L. Rock
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  2. W. A. Hagemoser
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  3. F. A. Osorio
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  4. H. A. McAllister
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Rock, D.L., Hagemoser, W.A., Osorio, F.A. et al. Transcription from the pseudorabies virus genome during latent infection. Archives of Virology 98, 99–106 (1988). https://doi.org/10.1007/BF01321010

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  • DOI: https://doi.org/10.1007/BF01321010

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