Summary
The major internal protein of the putative human type C virus SKA21-3 was compared with homologous proteins of mammalian type C viruses by two-dimensional analyses of radioiodinated tryptic peptides.
The SKA21-3 virus protein displayed the same pattern as the protein of simian sarcoma virus.
References
Nooter, K., Bentvelzen, P., Zurcher, C., Rhim, J.: Detection of human C-type “helper” viruses in human leukemic bone marrow with murine sarcoma virustransformed human and rat non-producer cells. Int. J. Cancer19, 59–65 (1977).
Koch, G., Nooter, K., Bentvelzen, P., Haaijman, J. J.: Serological characterization of a putative human C-type oncornavirus by means of the Sepharose bead immunofluorescence assay. Eur. J. Cancer13, 1397–1403 (1977).
Smith, R. G., Nooter, K., Bentvelzen, P., Robert-Guroff, M., Harewood, K., Reitz, M. S., Lee, S. A., Gallo, R. C.: Characterization of a type-C virus produced by co-cultures of human leukemic bone marrow and fetal canine thymus cells. Int. J. Cancer24, 210–217 (1979).
Sahagan, B. G., Haseltine, W. A.: Relationship of retroviruses isolated from human leukemia tissues to the woolly monkey-Gibbon ape leukemia viruses. J. Virol.34, 390–401 (1980).
Strand, M., August, J. T.: Structural proteins of mammalian RNA tumor viruses: Relatedness of the interspecies antigenic determinants of the major internal protein. J. Virol.15, 1332–1341 (1975).
Sherr, C. J., Fedele, L. A., Benveniste, R. E., Todaro, G. J.: Interspecies antigenic determinants of the reverse transcriptase and p30 proteins of mammalian type C viruses. J. Virol.15, 1440–1448 (1975).
Oroszlan, S., Gilden, R. V.: Amino acid sequences of plant and animal viral proteins. In:Fraenkel-Conrat, H., Wagner, R. R. (eds.), Comprehensive Virology, Vol. 13, 1–35. New York-London: Plenum Press 1979.
Wolfe, L. G., Smith, R. K., Deinhardt, F.: Simian sarcoma virus, type 1(Lagothrix): Focus assay and demonstration of nontransforming associated virus. J. Natl. Cancer Inst.48, 1905–1907 (1972).
Brouwer, J., Pluijms, W. J. M., Warnaar, S. O.: Chemical characterization of Rauscher leukemia virus proteins. J. gen. Virol.42, 415–421 (1979).
Kurland, C. G., Hardy, S. J. S., Mora, G.: Purification of ribosomal proteins fromEscherichia coli. In:Moldave, K., Grossman, L. (eds.), Methods in Enzymology, Vol. 20, 381–391. New York-London: Academic Press 1971.
Greenwood, F. G., Hunter, W. A., Glover, J. S.: The preparation of131Ilabeled human growth hormone of high specific activity. Biochem. J.89, 114–123 (1963).
Laemmli, U. K.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature227, 680–685 (1970).
Brouwer, J., Warnaar, S. O.: Analysis of the origin of charge heterogeneity of Rauscher murine leukemia virus p 30. J. gen. Virol.51, 409–414 (1980).
Robinson, A. B., Rudd, C. J.: Deamidation of glutaminyl and asparaginyl residues in peptides and proteins. In:Horecker, B. L., Stadtmann, E. R. (eds.), Current Topics in Cellular Regulation, Vol. 8, 247–295. New York-London: Academic Press 1974.
Gautsch, J. W., Elder, J. H., Schindler, J., Jensen, F. C., Lerner, R. A.: Structural markers on core protein p30 of murine leukemia virus: Functional correlation withFv-1 tropism. Proc. Natl. Acad. Sci. U.S.A.75, 4170–4174 (1978).
Author information
Authors and Affiliations
Additional information
With 3 Figures
Rights and permissions
About this article
Cite this article
Brouwer, J., den Dulk, J. Structural characterization of the major internal protein of the SKA 21-3 virus. Archives of Virology 69, 85–90 (1981). https://doi.org/10.1007/BF01315268
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01315268