Summary
Immunization of mice with a relatively small dose of subviral herpes simplex type 1 vaccine used prior to homotypic virus infection reduced the frequency of recurrent disease. However, the same vaccine dose administered after virus infection did not result in significant reduction of recurrences.
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References
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Šlichtová, V., Kutinová, L. & Vonka, V. Immunogenicity of a subviral herpes simplex type 1 preparation: Reduction of recurrent disease in mice. Archives of Virology 71, 75–78 (1982). https://doi.org/10.1007/BF01315176
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DOI: https://doi.org/10.1007/BF01315176