Summary
The inhibitory effect of N,N′-bis(methylisatin-β-thiosemicarbazone)-2-methylpiperazine (compound TSKI-VI) and methisazone (Marboran) on the growth of vaccinia virus (IHD strain) was studiedin vitro andin vivo. The therapeutic indices of both compounds determinedin vivo were similar, but TSKI-VI was found more efficientin vitro.
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Borysiewicz, J., Witaliński, W. Effect of N,N′-bis(methylisatin-β-thiosemicarbazone)-2-methylpiperazine on vaccinia virus replicationin vitro andin vivo . Archives of Virology 62, 83–86 (1979). https://doi.org/10.1007/BF01314907
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DOI: https://doi.org/10.1007/BF01314907