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Heterogeneity of primate foamy virus genomes

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Summary

DNA of the T-lymphotropic simian foamy virus (SFV) LK-3 was cloned in a plasmid vector and used as a probe in comparative DNA:DNA hybridization studies with primate foamy viruses (SFV serotypes 1, 2, 3, 5, 6, 7, 8, fresh SFV isolates from 12 African green monkeys and one rhesus monkey, as well as human syncytium forming virus). All freshly isolated viruses seemed to be variants of SFV types 2 and 3. Especially LK-3 appeared to be closely related to SFV type 3. No hybridization of the LK-3 clone was observed to DNA sequences of human immunodeficiency virus (HIV-1).

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References

  1. Achong BG, Mansell PWA, Epstein MA, Clifford P (1971) An unusual virus in cultures from a human nasopharyngeal carcinoma. J Natl Cancer Inst 46: 299–307

    Google Scholar 

  2. Flügel RM, Rethwilm A, Maurer B, Darai G (1987) Nucleotide sequence analysis of the ENV gene and its flanking regions of the human spumaretrovirus reveals two novel genes. EMBO J 6: 2077–2084

    Google Scholar 

  3. Haase AT (1986) Pathogenesis of lentivirus infections. Nature 322: 130–136

    Google Scholar 

  4. Hahn BH, Shaw GM, Arya SK, Popovic M, Gallo RC (1984) Molecular cloning and characterization of the HTLV-III virus associated with AIDS. Nature 312: 166–169

    Google Scholar 

  5. Hooks JJ, Gibbs CJ (1975) The foamy viruses. Bacteriol Rev 39: 169–185

    Google Scholar 

  6. Hubacek J, Glover SW (1970) Complementation analysis of temperature-sensitive host specificity mutations in Escherichia coli. J Mol Biol 50: 111–127

    Google Scholar 

  7. Loenen WAM, Brammer WJ (1980) A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes. Gene 40: 249–259

    Google Scholar 

  8. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

    Google Scholar 

  9. Messing J (1983) New M 13 vectors for cloning. Methods Enzymol 101: 20–79

    Google Scholar 

  10. Minowada J, Ohnuma T, Moore GE (1972) Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst 49: 891–895

    Google Scholar 

  11. Nara PL, Robey WG, Arthur LO, Gonda MA, Asher DM, Yanagihara R, Gibbs CJ Jr, Gajdusek DC, Fischinger PJ (1987) Simultaneous isolation of simian foamy virus and HTLV-III/LAV from chimpanzee lymphocytes following HTLV-III or LAV inoculation. Arch Virol 92: 183–186

    Google Scholar 

  12. Neumann-Haefelin D, Rethwilm A, Bauer G, Gudat F, zur Hausen H (1983) Characterization of a foamy virus isolated from Cercopithecus aethiops lymphoblastoid cells. Med Microbiol Immunol 172: 75–86

    Google Scholar 

  13. Neumann-Haefelin D, Schweizer M, Corsten B, Matz B (1986) Detection and characterization of infectious DNA intermediates of a primate foamy virus. J Gen Virol 67: 1993–1999

    Google Scholar 

  14. Polack A, Delius H, Zimber U, Bronkamm GW (1984) Two deletions in the Epstein-Barr virus genome of the Burkitt lymphoma nonproducer line Raji. Virology 133: 146–157

    Google Scholar 

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Schweizer, M., Corsten, B. & Neumann-Haefelin, D. Heterogeneity of primate foamy virus genomes. Archives of Virology 99, 125–134 (1988). https://doi.org/10.1007/BF01311030

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  • DOI: https://doi.org/10.1007/BF01311030

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