Summary
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1.
The tissue culture technique based upon development of cytopathic changes is a convenient and economical method to determine the pH and temperature ranges for inactivation of rinderpest virus.
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2.
The virus was rapidly inactivated at pH values of 3.0 and below, 11.0 and above, as well as at a temperature of 75° C and above.
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3.
Comparative tests in tissue cultures and in cattle suggest that the animal assay was the more sensitive one to demonstrate minute quantities of residual infectious virus.
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De Boer, C.J., Barber, T.L. pH and thermal stability of rinderpest virus. Archiv f Virusforschung 15, 98–108 (1964). https://doi.org/10.1007/BF01241425
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DOI: https://doi.org/10.1007/BF01241425