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Crystal and molecular structure of geiparvarin

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Abstract

The structure of the antitumor agent geiparvarin was determined by direct methods from CuKα diffractometer data. The crystals of synthetic geiparvarin have the space groupP21/c witha = 8.305(1),b = 11.077(1),c = 18.287(1) Å, β = 98.79(1) °, andZ = 4. The structure was refined toR = 0.047. The chemically determined structure was confirmed. Bond distances and angles are normal and there are no unusual C-H ⋯ O intermolecular contacts.

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Authors and Affiliations

  1. Department of Chemistry, Laboratory for Research on the Structure of Matter, and The Monell Chemical Senses Center, The University of Pennsylvania, 19104, Philadelphia, Pennsylvania

    Bruce H. Toder, Diane Boschelli & Amos B. Smith III

Authors
  1. Bruce H. Toder
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  2. Diane Boschelli
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  3. Amos B. Smith III
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Additional information

IUPAC name: 7-[3-(4,5-dihydro-5,5-dimethy1-4-oxo-2-furanyl)-2-butenyi]-oxy-(2H-1-benzopyran-2-one).

Camille and Henry Dreyfus Teacher-Scholar, 1978–1983; National Institutes of Health Career Development Award, 1980–1985.

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Toder, B.H., Boschelli, D. & Smith, A.B. Crystal and molecular structure of geiparvarin. Journal of Crystal and Molecular Structure 9, 189–198 (1979). https://doi.org/10.1007/BF01198554

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  • DOI: https://doi.org/10.1007/BF01198554

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