Skip to main content
SpringerLink
Log in

Reversible mesenteric vascular occlusion associated with oral contraceptives

  • Original Articles
  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

Abstract

Reversible mesenteric vascular occlusion should be considered in young women on oral contraceptives who present with abdominal pain and bloody diarrhea. A patient is described in whom these symptoms as well as small bowel changes on x-ray resolved spontaneously only after discontinuation of the contraceptives. During the acute illness, thickened mucosa with rigidity of the bowel loops, narrowing of the bowel lumen, and thumb printing were evident on small bowel series.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Reed DL, Coon WW: Thromboembolism in patients receiving progestational drugs. N Engl J Med 269:622–624, 1963

    Google Scholar 

  2. Kilpatrick ZM, Silverman JF, Betancourt E, Farman J, Lawson JP: Vascular occlusion of the colon and oral contraceptives N Engl J Med 278:438–440, 1968

    Google Scholar 

  3. Combs JW, Catt K, Seigel DG, Lipsett MB: NIH Conference—problems in contraception (pp 258–261). Ann Intern Med 74:251-263, 1971

    Google Scholar 

  4. Doll R, Crombie DL, Duncan AS, Hill AB, Inman WHW, Vessey MP: Risk of thromboembolic disease in women taking oral contraceptives. Br Med J 2:355–359, 1967

    Google Scholar 

  5. Brennan MF, Clarke AM, Macbeth WAAG: Infarction with the midgut associated with oral contraceptives. N Engl J Med 279:1213–1214, 1968

    Google Scholar 

  6. Hoyumpa AM, Schiffl, Helfman EL: Budd-Chiari syndrome in women taking oral contraceptives. Am J Med 50:137–140, 1971

    Google Scholar 

  7. Ecker JA, McKittrick JE, Farling RM: Thrombosis of the hepatic veins: the Budd-Chiari syndrome—a possible link between oral contraceptives and thrombosis formation. Am J Gastroenterol 45:429–443, 1966

    Google Scholar 

  8. Sterup K, Mosbech J: Budd-Chiari syndrome after taking oral contraceptives. Br Med J 4:660, 1967

    Google Scholar 

  9. Somayoji BN, Eeles GH, Paton A, Parker, RGF: Budd-Chiari syndrome after oral contraceptives. Br Med J 1:53–54, 1968

    Google Scholar 

  10. Rothwell-Jackson RL: Budd-Chiari syndrome after oral contraceptives. Br Med J 1:252, 1968

    Google Scholar 

  11. Clubb AW, Giles C: Budd-Chiari syndrome after oral contraceptives. Br Med J 1:252, 1968

    Google Scholar 

  12. Grayson MJ, Reilly MCT: Budd-Chiari syndrome after oral contraceptives. Br Med J 1:512–513, 1968

    Google Scholar 

  13. Larsson-Cohn U, Stenrom U: Jaundice during treatment with oral contraceptive agent. JAMA 193:422–426, 1965

    Google Scholar 

  14. Williams LF Jr: Vascular insufficiency of the bowels. Disease of the Month, August, 1970

  15. Nelson SW, Eggleston W: Findings on plain roentgenograms of the abdomen associated with mesenteric vascular occlusion with a possible new sign of mesenteric venous thrombosis. Am J Roentgenol Radium Ther Nucl Med 83:886–894, 1960

    Google Scholar 

  16. Cregg HA, Smith FG: Radiographic demonstration of localized mesenteric thrombosis: a case report. Radiology 61:379–381, 1953

    Google Scholar 

  17. Frimann-Dahl J: Roentgenographic examination in mesenteric thrombosis. Am J Roentgenol Radium Ther Nucl Med 64:610–616, 1950

    Google Scholar 

  18. Marshak RH, Lindner AE: Radiology of the Small Intestine, Philadelphia, W. B. Saunders Co, 1970, p 138

    Google Scholar 

  19. Reute SR, Kanter IE, Redman HK: Angiography in reversible colonic ischemia. Radiology 97:371–375, 1970

    Google Scholar 

  20. Friedenberg MJ, Polk HC Jr, McAlister WH, Shochat, SJ: Superior mesenteric arteriography in experimental mesenteric venous thrombosis. Radiology 85:38–45, 1965

    Google Scholar 

  21. Brakman P, Albrechtsen OK, Astrup T: Blood coagulation, fibrinolysis and contraceptive hormones. JAMA 199:69–74, 1967

    Google Scholar 

  22. Brakman P, Astrup T: Effects of female hormones used as oral contraceptives on fibrinolytic system in blood. Lancet 2:10–12, 1964

    Google Scholar 

  23. Thomson JM, Poller L: Oral contraceptive hormones and blood coagulability. Br Med J 2:270–273, 1965

    Google Scholar 

  24. Margulis RR, Ambrus JL, Mink IB: Progestational agents and blood coagulation. Am J Obstet Gynecol 93:161–166, 1965

    Google Scholar 

  25. Bolton CH, Hampton JR, Mitchell JRA: Effect of oral contraceptive agents on platelets and plasma-phospholipids. Lancet 1:1336–1341, 1968

    Google Scholar 

  26. Danforth DN, Manalo-Estrella P, Buckingham JC: The effects of pregnancy and of enovid on the rabbit vasculature. Am J Obstet Gynecol 88:952–962, 1964

    Google Scholar 

  27. Goodrich SM, Wood JE: Peripheral venous distensibility and velocity of blood flow during pregnancy or during oral contraceptive therapy. Am J Obstet Gynecol 90:740–744, 1964

    Google Scholar 

  28. Neistadt A, Schwartz RW, Schwartz SI: Norethynodrel with mestranol and venous blood flow. JAMA 198:784–785, 1966

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Medicine and Radiology, Baltimore City Hospitals, 4940 Eastern Ave., 21224, Baltimore, MD

    Bruce J. Nothmann MD, S. Chittinand MD &  Marvin M. Schuster MD, FACP

  2. Johns Hopkins University School of Medicine, Baltimore, Maryland

    Bruce J. Nothmann MD, S. Chittinand MD &  Marvin M. Schuster MD, FACP

Authors
  1. Bruce J. Nothmann MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Chittinand MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marvin M. Schuster MD, FACP
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nothmann, B.J., Chittinand, S. & Schuster, M.M. Reversible mesenteric vascular occlusion associated with oral contraceptives. Digest Dis Sci 18, 361–368 (1973). https://doi.org/10.1007/BF01071983

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01071983

Keywords

Search

Navigation