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Basic mechanisms determining the characteristics of calcium signals in nerve cells

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Abstract

The paper summarizes recent data about the mechanisms that determine the kinetics and amplitude of transient elevations in the intracellular level of free calcium (“calcium signals”) in excitable cells. The relative role of various types of voltage-operated calcium channels, fast cytosolic buffering, active accumulation in intracellular stores, and extrusion of ions from the cell are discussed. New technical approaches enabling resolution of these questions are described.

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Authors and Affiliations

  1. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kiev, Ukraine

    P. G. Kostyuk

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  1. P. G. Kostyuk
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Neirofiziologiya/Neurophysiology, Vol. 26, No. 1, pp. 5–8, January–February, 1994.

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Kostyuk, P.G. Basic mechanisms determining the characteristics of calcium signals in nerve cells. Neurophysiology 26, 3–6 (1994). https://doi.org/10.1007/BF01059985

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  • DOI: https://doi.org/10.1007/BF01059985

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