Skip to main content
Log in

Synthesis of derivatives of 1, 2, 4-triazole-3, 5-dicarboxylic acid

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

By oxidation of 3,5-dimethyl-1,2,4-triazole the monopotassium salt of 1,2,4-triazole-3,5-dicarboxylic acid was obtained. The mononitryl of 1,2,4-triazole-3,5-dicarboxylic acid was isolated during the reaction between 3-diazo-1,2,4-triazole-5-carboxylic acid and potassium cyanide in the presence of copper cyanide. Acid hydrolysis of 3-cyano-1,2,4-triazole-5-carboxylic acid leads to the formation of 3-carbamido-5-carboxy-1,2,4-trlazole, which on esterification with methanol gives rise to 3-carbamido-5-carbomethoxy-1,2,4-triazole.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. English patent no. 816531, 1959; Chemical abstracts,54, 1552, 1960.

    Google Scholar 

  2. G. I. Chipen and V. Ya. Grinshtein, Izv. AN Latv. SSR, ser. khim., 204, 1965.

  3. E. N. Zil'berman and A. E. Kulikova, ZhOKh,29, 3039, 1959.

    Google Scholar 

  4. I. Ya. Postovskii and N. N. Vereshchagina, ZhOKh, 29, 2139, 1959.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vereshchagina, T.N., Lopyrev, V.A., Pevzner, M.S. et al. Synthesis of derivatives of 1, 2, 4-triazole-3, 5-dicarboxylic acid. Chem Heterocycl Compd 5, 681–682 (1969). https://doi.org/10.1007/BF00957390

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00957390

Keywords

Navigation