Abstract
This case report describes infantile nephrotic syndrome (NS) in a baby girl with a clinically severe cytomegalovirus (CMV) infection. Culture of the baby's urine was positive for CMV and IgM anti-CMV antibodies were detected. After an unsuccessful course of corticosteroids, gancyclovir treatment was started and a remission of cutaneous, pulmonary, and renal symptoms was achieved. As the mother also developed NS at the end of pregnancy, a common etiology could be postulated, although there were no signs of recent CMV infection in the mother, only anti-CMV IgG. The relationship between CMV infection and glomerular disease is still unclear: NS may represent another manifestation of CMV disease.
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Giani, M., Edefonti, A., Damiani, B. et al. Nephrotic syndrome in a mother and her infant: relationship with cytomegalovirus infection. Pediatr Nephrol 10, 73–75 (1996). https://doi.org/10.1007/BF00863452
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DOI: https://doi.org/10.1007/BF00863452