References
Hyink DP, Abrahamson DR (1995) Origin of the glomerular vasculature in the developing kidney. Semin Nephrol 15:300–314
Abrahamson DR (1991) Glomerulogenesis in the developing kidney. Semin Nephrol 11:375–389
Clapp WL, Abrahamson DR (1994) Development and gross anatomy of the kidney. In: Tisher CC, Brenner BM (eds) Renal pathology, 2nd edn. Lippincott, Philadelphia, pp 3–59
Abrahamson DR, St. John PL (1992) Loss of laminin epitopes during glomerular basement membrane assembly in developing mouse kidneys. J Histochem Cytochem 40:1943–1953
Vanden Heuvel GB, Abrahamson DR (1993) Quantitation and localization of laminin A, B1, and B2 chain RNA transcripts in developing kidney. Am J Physiol 265:F293-F299
Vanden Heuvel GB, Leardkamolkarn V, St. John PL, Abrahamson DR (1996) Carboxy terminal sequence and synthesis of rat kidney laminin γl chain. Kidney Int (in press)
Hyink DP, Tucker DC, St. John PL, Leardkamolkarn V, Accavitti MA, Abrass CK, Abrahamson DR (1996) Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic kidneys. Am J Physiol (in press)
Santos OF, Barros EJG, Yang X-M, Matsumoto K, Nakamura T, Park M, Nigam SK (1994) Involvement of hepatocyte growth factor in kidney development. Dev Biol 163:525–529
Woolf AS, Kolarsk-Joannou M, Hardman P, Andermacher E, Moorby C, Fine LG, Jat PS, Noble MD, Gherardi E (1995) Role of hepatocyte growth factor/scatter factor and the m*et receptor in the early development of the metanephros. J Cell Biol 128: 171–184
Schmidt C, Bladt F, Goedecke S, Brinkman V, Zschiersche W, Sharpe M, Gherardi E, Birchmeier C (1995) Scatter factor/hepatocyte growth factor is essential for liver development. Nature 373:699–702
Uehara Y, Minowa O, Mori C, Shiota K, Kuno J, Noda T, Kitamura N (1995) Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 373: 702–705
Stark K, Vainio S, Vasileva G, McMahon AP (1995) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372:679–683
Nusse R, Varmus HE (1992) Wnt genes. Cell 69:1073–1087
Herzlinger D, Qiao J, Cohen D, Ramakrishna NM, Brown AM (1994) Induction of kidney epithelial morphogenesis by cells expressing Wnt-1. Dev Biol 166:815–818
Goodyer PR, Cybulsky A, Goodyer C (1993) Expression of the epidermal growth factor receptor in fetal kidney. Pediatr Nephrol 7:612–615
Rogers SA, Ryan G, Hammerman M (1992) Metamorphic transforming growth factor-alpha is required for fetal organogenesis in vitro. Am J Physiol 31:F533-F539
Goodyer PR, Dchbi M, Torban E, Bruening W, Pelletier J (1995) Repression of the retinoic acid receptor — alpha gene by the Wilms tumor suppressor gene product, WT1. Oncogene 10:1125–1129
Savill J (1994) Apoptosis and the kidney. J Am Soc Nephrol 5:12–21
Kopseki D (1993) Cell death programmed in uninduced metanephric mesenchymal cells. Pediatr Nephrol 7:609–611
Garcia-Porrero JA, Ojeda JL, Hurle JM (1978) Cell death during the postnatal morphogenesis of the normal rabbit kidney and in experimental renal polycystosis. J Anat 126:303–318
Koseki C, Herzlinger D, al-Awqati A (1992) Apoptosis in metanephric development. J Cell Biol 119:1327–1333
Coles HSR, Burne JF, Raff MC (1993) Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 118:777–784
McDonald RA, Miller JB, Sweeney WE, Coles HSR, Avner ED (1995) Apoptosis in murine autosomal recessive polycystic kidney disease (abstract). Pediatr Res 37:366A
LeBrun DP, Warnke RA, Cleary ML (1993) Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am J Pathol 142:743–753
Sorenson CM, Rogers SA, Korsmeyer SJ, Hammerman MR (1995) Fulminant metanephric apoptosis and abnormal kidney development in bcl-2 deficient mice. Am J Physiol 268:F73-F81
Boise LHH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G, Thompson CB (1993) Bcl-x: bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597–608
Krajewski S, Krajewski M, Shabaik A, Wang HG, Iric S, Fong L, Reed JC (1994) Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of bcl-2. Am J Pathol 145:1323–1336
Gasser B, Mauss Y, Ghnassia JP, Favre R, Kohler M, Yu O, Vonesch JL (1993) A quantitative study of normal nephrogenesis in the human fetus: its implication in the natural history of kidney changes due to low obstructive uropathies. Fetal Diagn Ther 8:371–384
El-Dahr SS, Gomez RA, Gray MS, Peach MJ, Carey RM, Chevalier RL (1994) In situ localization of renin and its mRNA in neonatal ureteral obstruction. Am J Physiol 258:F854-F862
Norwood VF, Carey RM, Geary KM, Jose PA, Gomez RA, Chevalier RL (1994) Neonatal ureteral obstruction stimulates recruitment of renin-secreting renal cortical cells. Kidney Int 45:1333–1339
Chevalier RL, Peach MJ (1985) Hemodynamic effects of enalapril on neonatal chronic partial ureteral obstruction. Kidney Int 28:891–898
Chung KH, Chevalier RL (1995) Arrested development of the neonatal kidney following chronic ureteral obstruction. J Urol (in press)
Carey AV, Carey RM, Gomez RA (1992) Expression of alphasmooth muscle actin in the developing kidney vasculature. Hypertension 19:168–175
Chung KH, Gomez RA, Chevalier RL (1995) Regulation of renal growth factors and clusterin by angiotensin AT1 receptors during neonatal ureteral obstruction. Am J Physiol 268:F1117-F1123
French LE, Wohlwend A, Sappino AP, Tschopp J, Schifferli JA (1994) Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death. J Clin Invest 93:877–884
Chevalier RL, Sturgill BC, Jones CE, Kaiser DL (1987) Morphologic correlates of renal growth arrest in neonatal partial ureteral obstruction. Pediatr Res 21:338–346
Chevalier RL, Kaiser DL (1984) Chronic partial ureteral obstruction in the neonatal guinea pig. I. Influence of urinephrectomy on growth and hemodynamics. Pediatr Res 18: 1266–1271
Zelikovic T, Chesney RW (1989) Sodium-coupled amino acid transport in renal tubule. Kidney Int 36:351–359
Weinman EJ, Dubinsky W, Shenolikar S (1989) Regulation of the renal Na+−H+ exchanger by protein phosphorylation. Kidney Int 36:519–525
Bertorello AM, Aperia A, Walaas SI, Naim AC, Greengard P (1991) Phosphorylation of the catalytic subunit of Na+, K+-ATPase inhibits the activity of the enzyme. Proc Natl Acad Sci USA 88:11359–11362
Wright EM, Hager KM, Turk E (1992) Sodium cotransport proteins. Curr Opin Cell Biol 4:696–702
Zelikovic I, Prezekwas J (1995) Ca++-dependent protein kinases modulate proline transport across the renal brush border membrane. Am J Physiol 268:F155-F162
Zelikovic I, Prezekwas J (1992) cAMP-dependent protein kinase modulates proline transport across the rat renal tubular luminal membrane. Pediatr Res 31:346
Zelikovic I, Orellana S, Miller J, Neff C, Mohr B (1995) Expression of a mutant regulatory subunit of cAMP-dependent protein kinase in MDCK cells prevents cAMP-mediated modulation of proline transport. Pediatr Res 37:375
Zelikovic I, Przekwas J (1993) The role of protein phosphorylation in renal amino acid transport. Pediatr Nephrol 7:621–629
Zelikovic I, Przekwas J, Miller J (1994) Difierential regulation of Ca++-dependent and Ca++-independent protein kinase C isoenzymes during kidney development. Pediatr Res 35:377
Bianchini L, Pouyssegur J (1995) Na+/H+ exchangers: structure, function and regulation. In: Schlondorff D, Bonventre J (eds) Molecular biology of the kidney in health and disease. Dekker, New York, p 415–425
Beck JC, Lipkowitz MS, Abramson RG (1991) Ontogeny of Na/H antiporter activity in rabbit renal brush border membrane vesicles. J Clin Invest 87:2067–2076
Guillery EN, Karniski LP, Mathews MS, Page WV, Orlowski J, Jose PA, Robillard JE (1995) Role of glucocorticoids in the maturation of renal cortical Na+/H+ exchanger activity during fetal life in sheep. Am J Physiol 268:F710-F717
Guillery EN, Karniski LP, Mathews MS, Robillard JE (1994) Maturation of proximal tubule Na+/H+ antiporter activity in sheep during the transition from fetus to newborn. Am J Physiol 267:F537-F545
Nakamura KT, Matherne GP, McWeeny OJ, Smith BA, Robillard JE (1987) Renal hemodynamics and functional changes during the transition from fetal to newborn life in sheep. Pediatr Res 21:229–234
Tumlin JA, Hoban CA, Medford RM, Sands JM (1994) Expression of Na-K-ATPase alpha- and b-subunit mRNA and protein isoforms in the rat nephron. Am J Physiol 266:F240-F245
Orlowski J, Lingrel JB (1988) Tissue-specific and developmental regulation of rat Na, K-ATPase catalytic alpha isoform and beta subunit mRNAs. J Biol Chem 236:10436–10442
Schwartz GJ, Evan AP (1984) Development of solute transport in rabbit proximal tubule. III. Na-K-ATPase activity. Am J Physiol 246:F845-F852
Fukuda Y, Aperia A (1988) Differentiation of Na+−K+ pump in rat proximal tubule is modulated by Na−−H+ exchanger. Am J Physiol 255:F552-F557
Schwartz GJ, Evan AP (1983) Development of solute transport in rabbit proximal tubule. I. HCO-3 and glucose absorption. Am J Physiol 245:F382-F390
Quigley R, Baum M (1990) Developmental changes in rabbit juxtamedullary proximal convoluted tubule bicarbonate permeability. Pediatr Res 28:663–666
Preisig PA, Ives HE, Cragoc EJ Jr, Alpern RJ, Rectro FC Jr (1987) Role of the Na+/H+ antiporter in rate proximal tubule bicarbonate absorption. J Clin Invest 80:970–978
Baum M (1992) Developmental changes in rabit juxtamedullary proximal convoluted tubule acidification. Pediatr Res 31:411–414
Baum M (1990) Neonatal rabbit juxtamedullary proximal convoluted tubule acidification. J Clin Invest 85:499–506
Baum M, Biemesdorfer D, Gentry D, Aronson P (1995) Ontogeny of rabbit renal cortical NHE-3 and NHE-1: effect of glucocorticoids. Am J Physiol (in press)
Baum M, Quigley R (1993) Glucocorticoids stimulate rabbit proximal convoluted tubule acidification. J Clin Invest 91: 110–114
Beck JC, Lipkowitz MS, Abramson RG (1991) Ontogeny of Na/H antiporter activity in rabbit renal brush border membrane vesicles. J Clin Invest 87:2067–2076
Baum M, Quigley R (1991) Prenatal glucocorticoids stimulate neonatal juxtamedullary proximal convoluted tubule acidification. Am J Physiol 261:F746-F752
Arar M, Levi M, Baum J (1994) Maturational effects of glucocorticoids on neonatal brush-border membrane phosphate transport. Pediatr Res 35:474–478
Spitzer A, Schwartz GJ (1992) The kidney during development. In: Windhager E (ed) Handbook of Physiology, renal physiology, vol 1. Oxford University Press, New York, pp 475–544
Barac-Nieto M, Dowd TL, Gupta RK, Spitzer A (1991) Changes in NMR visible kidney cell phosphate with age and diet: relationship to phosphate transport. Am J Physiol 261:F153-F162
Neiberger RE, Barac-Neito M, Spitzer A (1989) Renal reabsorption of phosphate during development: transport kinetics in BBMV. Am J Physiol 257:F268-F274
Barac-Nieto M, Corey H, Liu S-M, Spitzer A (1993) Role of intracellular phosphate in the regulation of renal Pi transport during development. Pediatr Nephrol 7:819–822
Magagnin S, Werner A, Markovich D, Sorribas V, Stange G, Biber J, Murer H (1993) Expression cloning of human and rat renal cortex Na/Pi cotransport. Proc Natl Acad Sci USA 90:5979–5983
Hammarlund K, Sedin G (1983) Transepidermal water loss in newborn infants. VIII. Relation to gestational age and post-natal age in appropriate and small for gestational age infants. Acta Paediatr Scand 72:721–728
Gruskay JA, Costarino AT, Polin RA, Baumgart S (1988) Nonoliguric hyperkalemia in the premature infant less than 1000 grams. J Pediatr 113:381–386
Stefano JL, Norman ME, Morales M, Chiavacci R, Coplung JM, Mishra OP, Delivoria-Papadopoulis M (1990) Intracellular cation flux as an etiology of non-oliguric hyperkalemia in the extremely low birth weight infant. Pediatr Res 27:227A
Costarino AT, Gruskay JA, Corcoran L, Polin RA, Baumgart S (1992) Sodium restriction versus daily maintenance replacement in very low birth weight premature neonates: a randomized, blind therapeutic trial. J Pediatr 120:99–106
Knauth A, Gordin M, McNelis W, Baumgart S (1989) A semipermeable polyurethane membrane as an artificial skin in the premature neonate. Pediatrics 83:945–950
Author information
Authors and Affiliations
Additional information
The American Society of Pediatric Nephrology (ASPN) is comprised of nephrologists in North America interested in the care of children and adolescents with kidney and urological diseases. The ASPN sponsors an annual educational symposium which is the major forum for the educational mission of the society. The following is a synopsis of the 1995 ASPN Educational Symposium. This symposium focussed upon developmental renal physiology and function.
Rights and permissions
About this article
Cite this article
Friedman, A.L., Satlin, L. & Trachtman, H. Proceedings of the American Society of Pediatric Nephrology Educational Symposium, San Diego, California, 7 May 1995. Pediatr Nephrol 10, 236–244 (1996). https://doi.org/10.1007/BF00862091
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00862091