Skip to main content
Log in

Squamous cell carcinoma of the brain with sarcoma-like stroma

  • Case Report
  • Published:
Virchows Archiv A Aims and scope Submit manuscript

Summary

A cerebral neoplasm containing a well differentiated epidermoid cyst surrounded by islands of infiltrating squamous cell carcinoma and a pleomorphic spindle cell stroma was described. By immunoperoxidase staining all these components contained keratin. The lesion was therefore similar to malignant squamous cell lesions with sarcoma-like stroma occurring in other body sites.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Battifora H (1976) Spindle cell carcinoma. Cancer 37:2275–2282

    Google Scholar 

  • Burger PC, Vogel FS (1982) Surgical pathology of the nervous system and its covering (2nd ed). J Wiley and Sons New York, pp 375–378

    Google Scholar 

  • Du Boulay CEH, Isaacson P (1981) Carcinoma of the oesophagus with spindle cell features. Histopathology 5:403–414

    Google Scholar 

  • Enrile FT, de Jesus PO, Bakst AA, Baluyot R (1973) Pseudosarcoma of the esophagus (polipoid carcinoma of esophagus with pseudosarcomatous features). Cancer 31:1197–1202

    Google Scholar 

  • Espinoza CC, Azar HA (1982) Immunohistochemical localization of keratin-type proteins in epithelial neoplasms. Am J Clin Pathol 78:500–507

    Google Scholar 

  • Gabbiani G, Kapanci Y, Barazzone P, Franke WW (1981) Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol 104:206–216

    Google Scholar 

  • Garcia CA, McGarry PA, Rodriguez F (1981) Primary intracranial squamous cell carcinoma of the right cerebellopontine angle. J Neurosurg 54:824–828

    Google Scholar 

  • Giangaspero F, Baruzzi G, Lemma E, Lorenzini P, Minghetti G, Ferracini R (1978) Carcinomi fusocellulari del laringe. Pathologica 70:537–545

    Google Scholar 

  • Goellner JR, Devine KD, Weiland LH (1973) Pseudosarcoma of the larynx. Am J Clin Pathol 59:312–326

    Google Scholar 

  • Kernohan JW, Uihlein A (1962) Sarcomas of the Brain. CC Thomas, Springfield, pp 25–69

    Google Scholar 

  • Leifer C, Miller AS, Putong PB, Min BH (1974) Spindle-cell carcinoma of the oral mucosa. A light and electron microscopic study of apparent sarcomatous metastases to cervical lymph nodes. Cancer 34:597–605

    Google Scholar 

  • Miettinen M, Lheto VP, Virtanen I (1982) Keratin in the epithelial-like cells of classical bifasic synovial sarcoma. Virchows Arch [Cell Pathol] 40:157–161

    Google Scholar 

  • Minkler DS, Meligro CH, Norris HT (1970) Carcinosarcoma of the larynx. Case report with metastases of epidermoid and sarcomatous elements. Cancer 26:195–200

    Google Scholar 

  • Osamura RY, Shimamura K, Hata J, Tomaoki N, Watanabe K, Kubota M, Yamazaki S, Mitomi T (1978) Polipoid carcinoma of esophagus. A unifying term for “carcinosarcoma” and “pseudosarcoma”. Am J Surg Pathol 2:201–208

    Google Scholar 

  • Piscioli F, Aldovini D, Bondi A, Eusebi V (1984) Squamous cell carcinoma with sarcoma-like stroma of the paranasal sinuses. Histopathology (in press)

  • Rojas-Espinosa O, Dannenberg AM, Sternberger LA, Tsuda T (1974) The role of cathepsin D in the pathogenesis of tubercolosis. Am J Pathol 74:1–18

    Google Scholar 

  • Steeper TA, Piscioli F, Rosai J (1983) Squamous cell carcinoma with sarcoma-like stroma of the female genital tract. Cancer 52:890–898

    Google Scholar 

  • Stener B, Kock NG, Petterson S, Zetterlund B (1967) Carcinosarcoma of the esophagus. J Thorac Cardiovasc Surg 54:746–750

    Google Scholar 

  • Sienski W, Dorsett B, Ioachim HL (1981) Identification of prekeratin by immunofluorescence staining in the differential diagnosis of tumors. Hum Pathol 12:452–458

    Google Scholar 

  • Stromeyer F (1909) Ober ein mit Sarkom kombiniertes Cholesteatom des Gehirns. Beitr Pathol Anat Pathol 47:392–398

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Giangaspero, F., Manetto, V., Ferracini, R. et al. Squamous cell carcinoma of the brain with sarcoma-like stroma. Vichows Archiv A Pathol Anat 402, 459–464 (1984). https://doi.org/10.1007/BF00734642

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00734642

Key words

Navigation