Summary
The Norwegian pancreas transplantation programme was initiated in June 1983. By November 1990, a total of 77 pancreatic transplantations had been performed, 63 simultaneously with a renal transplant. Five patients received pancreatic grafts after previous renal grafting while nine non-uraemic diabetic patients received pancreatic grafts only. In April 1988, the surgical technique was changed from duct-occluded segmental pancreas to whole pancreas grafting with duodenocystostomy. In recipients ofcombined grafts from the first group (segmental pancreatic grafts), the 1- and 5-year survival rates were 96% and 90% for the patients, 84% and 69% for renal grafts and 66% and 45% for pancreatic grafts. In the second group (whole pancreatic grafts with duodenocystostomy), the 6-month and 2-year survival rates were 87% at both intervals for the patients, 87% and 75% for both grafts. However, even though the bladder drainage technique allows isolated pancreas graft rejection to be diagnosed, the results ofisolated pancreas grafting were not improved by this technique, and most of these grafts were lost in therapy-resistant graft rejection.
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Abendroth D, Illner WD, Landgraf R, Land W (1990) A different clinical course of IDDM patients after simultaneous pancreas and kidney transplantation and kidney grafting alone. Transplant Proc 22:1579
Brekke IB, Holdaas H, Albrechtsen D, Fauchald P, Flatmark A (1990) Combined pancreatic and renal transplantation:improved survival of uremic diabetic patients and renal grafts. Transplant Proc 22:1580
Frohnert PP, Velosa JA, Munn SR, Marsh CL, Perkins JO (1990) Morbidity during the first year after pancreas transplantation. Transplant Proc 22:577
Mellert J, Hopt UT, Busing M, Holzer H (1990) Differential immunosuppressive strategies after combined pancreaticoduodenal and isolated kidney transplantation. Transplant Proc 22:1584–1585
Nakache R, Tyden G, Groth C-G (1989) Quality of life in diabetic patients after combined pancreas-kidney or kidney transplantation. Diabetes 38 (Suppl. 1):40–42
Sollinger HW, Stratta RJ, D'Alessandro AM et al. (1988) Experience with simultaneous pancreas-kidney transplantation. Ann Surg 208:475–482
Sutherland DER, Moudry-Munns KC (1990) International pancreas Transplantation Registry analysis. Transplant Proc 22:571–574
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Brekke, I.B. Indications and results of pancreatic transplantation: the Oslo experience 1983–1990. Diabetologia 34 (Suppl 1), S18–S20 (1991). https://doi.org/10.1007/BF00587612
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DOI: https://doi.org/10.1007/BF00587612