Summary
Voltage clamp experiments carried out on nodes of Ranvier of myelinated fibres ofRana esculenta showed that a small fraction of sodium channels fail to inactivate. Thus during long lasting depolarizing pulses there is a small Na-current superimposed on the leakage and potassium currents. This late Na-current appears more marked in sensory fibres than in motor ones.
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References
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Supported by grants of the C.N.R.S. and D.G.R.S.T.
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Dubois, J.M., Bergman, C. Late sodium current in the node of Ranvier. Pflugers Arch. 357, 145–148 (1975). https://doi.org/10.1007/BF00584552
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DOI: https://doi.org/10.1007/BF00584552