Summary
1. The antimicrobial activity of valinomycin and its analogs and also their capacity for forming complexes with potassium and sodium ions in solution have been investigated.
2. It has been shown that the capacity of CDPs of the valinomycin series for forming complexes with potassium ions is a necessary, but not sufficient, condition for the manifestation of antimicrobial activity by these compounds.
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Deceased.
M. M. Shemyakin Institute of the Chemistry of Natural Compounds, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 241–248, March–April, 1973.
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Shemyakin, M.M., Vinogradova, E.I., Ryabova, I.D. et al. Relationship between structure, stability of potassium complexes, and antimicrobial activity in a series of analogs of valinomycin. Chem Nat Compd 9, 229–234 (1973). https://doi.org/10.1007/BF00563351
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DOI: https://doi.org/10.1007/BF00563351