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Entstehung komplementbindender Antikörper in mit Kardiolipin stimulierten Lymphocytenkulturen Syphilis-Kranker

Complement binding antibodies in cardiolipin-stimulated lymphocyte cultures from patients with syphilis

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Summary

Lymphocyte cultures of syphilitic and control patients were stimulated by corpuscular cardiolipin. It could be demonstrated, that lymphoblasts, which were found in cultures of syphilitic patients, contain complement-binding antibodies reactive to cardiolipin and Reiter-antigen. Lymphoblasts containing such antibodies could not be found neither in unstimulated cultures of syphilitic patients, nor in lymphocyte cultures of healthy controls.

Zusammenfassung

Die Verfasser haben Lymphocytenkulturen von syphilitischen und gesunden Kontrollindividuen mit corpusculärem Kardiolipin-Antigen stimuliert und nachgewiesen, daß die in den Kulturen der Syphiliskranken befindlichen Lymphoblasten komplementbindende Antikörper enthalten, welche mit Kardiolipin und Reiter-Antigen in Reaktion treten. Derartige Antikörper enthaltende Lymphoblasten wurden weder in den nicht stimulierten Kulturen Syphiliskranker, noch in den Lymphocytenkulturen der gesunden Kontrollpersonen gefunden.

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Authors and Affiliations

  1. Universitäts-Hautklinik Szeged, Ungarn

    J. Hunyadi, A. Dobozy & N. Simon

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  1. J. Hunyadi
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  2. A. Dobozy
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  3. N. Simon
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Hunyadi, J., Dobozy, A. & Simon, N. Entstehung komplementbindender Antikörper in mit Kardiolipin stimulierten Lymphocytenkulturen Syphilis-Kranker. Arch. klin. exp. Derm. 239, 282–287 (1970). https://doi.org/10.1007/BF00520342

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  • DOI: https://doi.org/10.1007/BF00520342

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