Abstract
The resistance of mainly gram-negative bacteria against antibiotics is discussed with respect to new discoveries on the permeability barrier of the outer membrane. Proteins originally characterized as virus receptors have been found to be involved in the translocation of certain substrates across the membrane. Antibiotics can reach their target by the same “pores”.
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Braun, V. Membranpermeation und Antibiotika-Resistenz bei Bakterien. Naturwissenschaften 64, 126–132 (1977). https://doi.org/10.1007/BF00450570
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DOI: https://doi.org/10.1007/BF00450570