Abstract
Nine consecutive patients who underwent syringe-assisted liposuction with a mean aspirate volume of 3633 mL (range: 1800–5500) had their lipids, lipoproteins, and sex hormones measured pre- and postoperatively. Seven of the patients also underwent an oral glucose tolerance test with measurements of insulin and C-peptide. The major finding was a significant increase in HDL cholesterol and apolipoprotein A1, while there was no significant change in sex hormones or glucose levels 9–12 months after the liposuction procedure. The results indicate that large-volume liposuction might decrease the risk of cardiovascular disease in these patients.
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References
Björntorp P: Obesity and diabetes. In: Alberti KGMM, Krall LP (eds): The Diabetes Annual, Volume 5, Amsterdam: Elsvier, 1990
DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173, 1991
Denke MA, Sempos CT, Grundy SM: Excess body weight: an unrecognized cause of high blood cholesterol. Circulation 82: 228, 1990
Evans DJ, Hofmann RG, Kalkhoff RK, Kissebah AH: Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women. Metabolism 33: 68, 1984
Fournier PF: Why the syringe and not the suction machine? J Dermatol Surg Oncol 14: 1062, 1988
Friedewald WT, Levy RJ, Fredrichson DS: Estimation of the concentration of low-density-lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge. Clin Chem 18: 499, 1972
Grazer FM: Body contouring. In: McCarthy XX (ed): Plastic Surgery. Philadelphia: W.B. Saunders, 1990, pp 3964–4028
Landin K, Lønnroth P, Krotkiewski M, Holm G, Smith U: Increased insulin resistance and fat cell lipolysis in obese but not lean women with a high waist/hip ratio. Eur J Clin Invest 20: 530, 1990
Lillioja S, Bogardus C, Mott DM, Kennedy AL, Knowler WC, Howard BV: Relationship between insulin-mediated glucose disposal and lipid metabolism in man. J Clin Invest 75: 1106, 1985
Peterson B: Gender-an important parameter in medical science. Ugeskr Laeger 155: 608, 1993
Riepponen P, Marnierni J, Rautaoja T: Immunoturbidimetric determination of apolipoproteins A-1 and B in serum. Scand J Clin Lab Invest 47: 739, 1987
Samdal F, Mjolnerod OK, Lundbom J, et al: Gynecomastia: investigation and surgical treatment. Tidsskr Nor Laegeforen 109: 3015, 1989
Samdal F, Amland PF, Bugge JF: Blood loss during liposuction using the tumescent technique. Aesth Plast Surg 18: 157–160, 1994
Thorell A, Efendic S, Gutniak M, Häggmark T, Ljungqvist O: Development of postoperative insulin resistance is associated with the magnitude of operation. Eur J Surg 159: 593, 1993
Wing R, Bunker C, Kuller L, Matthews A: Insulin, body mass index, and cardiovascular risk factors in premenopausal women. Arteriosclerosis 9: 479, 1989
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Samdal, F., Birkeland, K.I., Ose, L. et al. Effect of large-volume liposuction on sex hormones and glucose- and lipid metabolism in females. Aesth. Plast. Surg. 19, 131–135 (1995). https://doi.org/10.1007/BF00450248
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DOI: https://doi.org/10.1007/BF00450248