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The prophylactic use of antibiotics in alloarthroplasty of the hip joint for coxarthrosis

A randomized study

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Summary

In alloarthroplasty of the hip joint due to coxarthrosis a randomized prospective controlled study was performed to test the efficiency of prophylactic antibiotics in reducing the postoperative infection rate. The minimum follow-up time was 730 days.

There were three infections (two superficial and one deep) in the group who received antibiotics (105 patients), 10 infections (two superficial and eight deep) in the control group (89 patients). The overall rates of infections and also the rate of the deep wound infections were significantly lower in patients who received prophylactic antibiotics.

Zusammenfassung

In einer randomisierten prospektiven Studie wurde beim totalendoprothetischen Hüftgelenkersatz die Wirksamkeit einer Antibiotika-Prophylaxe geprüft. Die Nachuntersuchungszeit betrug mindestens 730 Tage.

Bei 105 Patienten der behandelten Gruppe zeigten sich 3 Wundinfektionen (2x oberflächlich, 1x tief), bei 89 Patienten der Kontrollgruppe 10 Wundinfektionen (2x oberflächlich, 8x tief). Zwischen beiden Kollektiven ist der Unterschied der Gesamtinfektionsrate sowie der tiefen Wundinfektionen statistisch signifikant.

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Authors and Affiliations

  1. Orthopedic University Clinic Düsseldorf, Moorenstr. 5, D-4000, Düsseldorf, Germany

    K. P. Schulitz & W. Winkelmann

  2. Othhopedic University Clinic Heidelberg, Schlierbacher Landstr. 200a, D-6900, Heidelberg, Germany

    B. Schoening

Authors
  1. K. P. Schulitz
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  2. W. Winkelmann
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  3. B. Schoening
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Schulitz, K.P., Winkelmann, W. & Schoening, B. The prophylactic use of antibiotics in alloarthroplasty of the hip joint for coxarthrosis. Arch. Orth. Traum. Surg. 96, 79–82 (1980). https://doi.org/10.1007/BF00433285

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  • DOI: https://doi.org/10.1007/BF00433285

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