References
Brouty-Boye D, Gresser I (1981) Reversibility of the transformed and neoplastic phenotype. I. Progressive reversion of the phenotype of X-ray-transformed C3H/10T 1/2 cells under prolonged treatment with interferon. Int J Cancer 28:165–173
DeMaeyer E, Galasso G, Schellekens H (eds) (1981) The biology of the interferon System. Elsevier, Amsterdam
DeMaeyer E, DeMaeyer-Guignard J (1980) Host phenotype influences immunomodulation by interferon. Nature 284:173–175
Derynck R, Content J, DeClerque E, Volckart G, Tavernier J, Davos R, Fiers W (1980) Isolation and structure of a human fibroblast interferon gene. Nature 285:542–546
Fleischmann WR, Jr, Georgiades JA, Osborne LC, Johnson HM (1980) Potentiation of antitumor effect of virus-induced interferon by mouse immune interferon preparations. J Natl Cancer Inst 65:963–966
Gidlund N, Oern A, Wigzell H, Senik A, Gresser I (1978) Enhanced NK cell activity in mice injected with interferon and interferon inducers. Nature 273:759–761
Gresser I (1978) Antitumor effects of interferon. Biochim Biophys Acta 516:231–247
Gresser I, DeMaeyer-Guignard J, Tovey MG, DeMaeyer E (1979) Electrophoretically pure mouse interferon exerts multiple biologic effects. Proc Natl Acad Sci USA 76:5308–5312
Hanley DF, Wiranowska-Stewart M, Stewart II WE (1979) Pharmacology of interferons. I. Pharmacologic distinctions between human leucocyte and fibroblast interferons. Int J Immunopharmacol 1:219–226
Heron I, Hokland M Berg K (1978) Enhanced expression of β2 microglobulin and HLA antigens on human lymphoid cells by interferon. Proc Natl Acad Sci USA 75:6215–6219
Hewitt HB (1978) The choice of animal tumors for experimental studies of cancer therapy. Adv Cancer Res 27:149–200
Hirt HM, Becker H, Kirchner H (1978) Induction of interferon production in mouse spleen cell cultures by Corynebacterium parvum Cell Immunol 38:168–175
Horning SJ, Levine JF, Miller RA, Merigan TC (1981) Clinical and Immunologic effects of recombinant leukocyte A interferon in eight patients with advanced cancer. Presented at the Second Annual International Congress for Interferon Research. October 21–23, San Francisco, USA
Huang KY, Donahoe RM, Gordon FB, Dressler H (1971) Enhancement of phagocytosis by interferon containing preparations. Infect Immun 4:581–588
Kirchner H (1981) Logistics of tumor immunology. Klin Wochenschr (in press) Klein G (1973) Tumor immunology. Transplant Proc 5:31–41
Lindenmann J (1981) Perspektiven der Interferon-Forschung. Naturwissenschaften 68:9–13
Lucero MA, Fridman WH, Prevost MA, Billardon, C, Pouillart P, Dumont J, Falcoff E (1981) Effect of various interferons on the spontaneous cytotoxicity exerted by lymphocytes from normal and tumor-bearing patients. Cancer Res 41:294–299
Marcucci F, Waller M, Kirchner H, Krammer P (1981) Production of immune interferon (IFN-γ) by murine T-cell clones from long-term cultures. Nature 291:79–81
Munk K, Kirchner H (eds) (1982) Interferon: Properties, mode of action, production and clinical application. Karger Basel (in press)
Nagata S, Mantei N, Weissmann Ch (1980) The structure of one of the eight or more distinct chromosomal genes for human interferon. Nature 287:401–408
Nathan H, Groopman JE, Quan SG, Bersch N, Golde DW (1981) Immune (γ) interferon produced by a human T-lymphoblast cell line. Nature 292:842–844
Newmark P (1981) Nature editorial: Interferon. Decline and stall Nature 291:105–106
Scott GM, Secher DS, Flowers D, Bate J, Cantell K, Tyrrell DAJ (1981) Toxicity of interferon. Br Med J 282:1345–1348
Taniguchi T, Mantei N, Schwarzstein M, Nagata S, Maramatsu M, Weissmann Ch (1980) Human leucocyte and fibroblast interferon are structurally related. Nature 285:547–549
Author information
Authors and Affiliations
Additional information
The “Journal of Cancer Research and Clinical Oncology” publishes in loose succession “Editorials” and “Guest Editorials” on current and/or controversial problems in experimental and clinical oncology. These contributions represent exclusively the personal opinion of the author. The Editors Die Zeitschrift “Journal of Cancer Research and Clinical Oncology” bringt in zwangloser Folge “Editorials” und “Guest Editorials” zu aktuellen und/oder kontroversen Problemen der experimentellen und klinischen Onkologie. Diese Beiträge geben ausschließlich die persönliche Meinung des Autors wieder.
Rights and permissions
About this article
Cite this article
Kirchner, H. Interferons as antitumor agents. J Cancer Res Clin Oncol 103, 1–6 (1982). https://doi.org/10.1007/BF00410300
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00410300