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Cilia in normal and regenerating islet tissue

An ultrastructural study in the Chinese hamster with particular reference to the β-cells and the ductular epithelium

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Summary

Ciliated cells occasionally occur in pancreatic ductule cells and islet β-cells of normal Chinese hamsters. In the regenerating pancreatic parenchyma of alloxan-treated Chinese hamsters an increased amount of cilia is observed in the ductule cells and islet β-cells. No obvious cilia were found in the other pancreatic cell types of normal and alloxan-treated animals. One and the same ductule cell possesses one, two, or rather often many cilia protruding into the ductule lumen. In the islet β-cells there are one or two cilia that often extend into intercellular spaces. The fibre arrangement varies in different parts of the cilia. The basic fibre pattern seems to be 9 + 2, the 9 peripheral fibres consisting of 2 subfibres, and the 2 central being single. The basal bodies (centrioles) consist of 9 groups of 2 or 3 aligned tubular elements. Filaments are associated with the centrioles. The functional significance of the cilia is discussed.

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This work was supported by grants from the Swedish Medical Research Council (Projects No. K67-12X-718-02 and K68-12X-718-03) and the Medical Faculty, University of Umeå.

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Boquist, L. Cilia in normal and regenerating islet tissue. Z. Zellforsch. 89, 519–532 (1968). https://doi.org/10.1007/BF00336177

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  • DOI: https://doi.org/10.1007/BF00336177

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