Summary
Previous studies have shown that the mutT, mutH and mutL mutators of Escherichia coli have a marked advantage in competition growth with otherwise coisogenic wild-type strains. As shown in this paper the same is true for the mutS mismatch mutator. In three experiments mutS could outgrow the wild-type and had higher fitness values.
This is a preview of subscription content, log in via an institution to check access.
References
Chao L, Cox EC (1983) Competition between high and low mutating strains of Escherichia coli. Evolution 37:125–134
Cox EC, Gibson TC (1974) Selection for high mutation rates in chemostats. Genetics 77:169–184
Gibson TC, Scheppe ML, Cox EC (1970) Fitness of an Escherichia coli mutator gene. Science 169:686–688
Nestmann ER, Hill RF (1973) Population changes in continuously growing mutator cultures of Escherichia coli. Genetics [suppl] 73:41–44
Rydberg B (1978) Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli. Mutat Res 52:11–24
Tröbner W, Piechocki R (1981) Competition growth between Escherichia coli mutL and mut + in continuously growing cultures. Z Allg Mikrobiol 21:347–349
Author information
Authors and Affiliations
Additional information
Communicated by H. Böhme
Rights and permissions
About this article
Cite this article
Tröbner, W., Piechocki, R. Competition between isogenic mutS and mut + populations of Escherichia coli K12 in continuously growing cultures. Molec Gen Genet 198, 175–176 (1984). https://doi.org/10.1007/BF00328719
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00328719