Abstract
In a series of 20 patients with a proven diagnosis of myeloma, both full radiographic skeletal surveys and full ratio-nuclide bone images were performed. When these were compared, they showed that (i) imaging underestimated the number of areas involved by 50%, but there were no false negative whole images when compared with the radiology, (ii) large lytic areas on X-ray show as ‘cold’ areas on the bone image but small ones show as normal, (iii) images that show areas of increased uptake (‘hot’) are almost always associated with fracture, and (iv) patients with bone pain very commonly had ‘hot’ images corresponding to the region of pain.
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4th year medical student
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Frank, J.W., LeBesque, S. & Buchanan, R.B. The value of bone imaging in multiple myeloma. Eur J Nucl Med 7, 502–505 (1982). https://doi.org/10.1007/BF00257216
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DOI: https://doi.org/10.1007/BF00257216