References
Al-Sarraf, M., Sardesai S., Vaitkevicius, V. K.: Clinical immunologic responsiveness in malignant disease. (2) In vitro response to phytohemagglutinin and the effect of cytotoxic drugs. Oncology 26, 357 (1972)
Bolton, P. A., Mander, A. M., Davidson, J. M., James, S. L., Necombre, R. G., Hughes, L. E.: Cellular immunity in cancer: comparison of delayed hypersensitivity skin tests in three common cancers. Brit. med. J. 1975 II, 18
Bonmassar, E., Testorelli, C., Franco, P., Goldin, A., Cudkowicz, G.: Changes of the immunogenic properties of a radiation-induced mouse lymphoma following treatment with antitumor drugs. Cancer Res. 35, 1957 (1975)
Borella, L., Green, A. A., Webster, R. G.: Immunologic rebound after cessation of long-term chemotherapy in acute leukemia. Blood 40, 42 (1972)
Campanile, F., Gaston, M., Bonmassar, E., Goldin, A.: Increased immunogenicity of two lymphomas following treatment with dimethyl trizeno-imidazole-carboxamide (TIC) in athymic-nude mice. Proc. Amer. Ass. Cancer. Res. 16, 36 (Abstract 142) (1975)
Cardozo, E. L.: The effect of cytostatic therapy with cyclophosphamide alone or in combination with methotrexate on the PHA lymphocyte culture and on the immunoglobulins. Oncology 24, 261 (1970)
Cheema, A. R., Hersh, E. M.: Patient'survival after chemotherapy and its relationship to in vitro lymphocyte blastogenesis. Cancer 28, 851 (1971)
Clarysse, A., Kenis, Y., Mathé, G.: Cancer chemotherapy. Its role in the treatment strategy of hematologic malignancies and solid tumors. Berlin-Heidelberg-New York: Springer 1976
Ezdinli, E., Simonson, K., Icli, F., Kerman, R.: Effects of single versus multiple agent therapy on cell-mediated immunity. Proc. Amer. Soc. Oncol. 18, 355 (Abstract C-353) (1977)
Fidler, I. J.: Experimental basis for immunotherapy of metastatic disease. In: Immunotherapy of Human Cancer. 22nd Annual Clinical Conference, Houston (in press, 1978)
Fujimoto, S., Greene, M. I., Sehon, A. H.: Regulation of the immune response to tumor antigens. I. Immunosuppressor cells in tumorbearing hosts. J. Immunol. 116, 791 (1976a)
Fujimoto, S., Greene, M. I., Sehon, A. H.: Regulation of immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts. J. Immunol. 116, 800 (1976b)
Geffard, M., Orbach-Arbouys, S.: Enhancement of T suppressor activity in mice by high doses of BCG. Cancer Immunol. Immunother. 1, 41 (1976)
Goldin, A., Houchens, D. P.: Chemotherapy modalities and immune condition of the host. In: Antibiotics Chemotherapy. Bâle: Karger (in press), (1978)
Goodwin, J. S., Messner, R. P., Bankhurst, A. D., Peake, G. T., Saiki, J. H., Williams, R. C., Jr.: Prostaglandium-producing suppressor cells in Hodgkin's disease. New Engl. J. Med. 297, 963 (1977)
Gorczynski, R. M., Norbury, C.: Suppressor cells in murine sarcoma virus induced tumors. Cells in immunity. International Symposium, London, p. 149. Ontario: University of Western Ontario Press 1975
Harris, J. K., Bagai, R. C., Stewart, T. H. M.: Serial monitoring of immune reactivity in cancer patients receiving chemotherapy as a means of predicting anti-tumor response. Proc. 7th Leucocyte Culture Congress. Daguillard, F. (ed.), p. 433. New York: Academic Press 1973
Hersh, E. M.: Clinical rationale for immunotherapy and integration of immunotherapy into the strategy of cancer treatment. In: Immunotherapy of human cancer. 22nd Annual Clinical Conference, Houston, 1977 (in press, 1978)
Hersh, E. M., Oppenheim J. J.: Inhibition of in vitro lymphocyte transformation during chemotherapy in man. Cancer Res. 27, 98 (1967)
Houchens, D. P., Bonmassar, E., Gaston, M., Goldin, A.: Drugmediated immunogenic changes of virus-induced leukemias in vivo. Cancer Res. 36, 1347 (1976)
Imbach, J. L., Montero, J. L., Moruzzi, A., Serrou, B., Chenu, E., Hayat, M., Mathé, G.: The oncostatic and immunosuppressive action of new nitrosourea derivatives containing sugar radicals. Biomedicine 23, 410 (1975)
Jones, K. D., Whitehead, R. H., Grimshaw, D., Hughes, L. E.: Lymphocyte response to chemotherapy in breast cancer (unpublished)
Joseph, R. R., Belpomme, D., Mathé, G.: Increase in “null” cells in acute lymphocytic leukaemia in remission on long-term immunotherapy. Brit. J. Cancer 33, 567 (1976)
Kirchner, H., Chused, T. M., Herberman, R., et al.: Evidence of suppressor cell activity in spleen of mice bearing primary tumors induced by moloney sarcoma virus. J. exp. Med. 139, 1473 (1974)
Lespinats, G., Poupon, M. F.: Données récentes sur l'immunologie des tumeurs. Mécanismes d'échappement au contrôle immunologique. Rôle des cellules suppressives. Bull. Cancer (Paris) 63, 269 (1976)
Leventhal, B. G., Cohen, P., Triem, S. C.: Effect of chemotherapy on the immune response in acute leukemia. Israel J. med. Sci. 10, 866 (1974)
Lubet, R. A., Carlson, D. E.: Tumor immunity directed against MOPC 104E: Effect of various therapeutic regimens. Cancer Immunol. Immunother. 2, 267 (1977)
Maguire, H. C.: Increased tumor immunity with cyclophosphamide. Proc. Amer. Ass. Cancer Res. 18, 185 (Abstract 738) (1977)
Mantovani, A.: In vitro and in vivo cytotoxicity of adriamycin and daunomycin for murine macrophages. Cancer Res. 37, 815 (1977)
Mantovani, A., Tagliabue, A., Vecchi, A., Spreafico, F.: Effects of adriamycin and daunomycin on spleen cell populations in normal and tumor allografted mice. Europ. J. Cancer 12, 381 (1976)
Mathé, G.: Cancer active immunotherapy. Immunoprophylaxis and immunogrestoration. An introduction. Berlin-Heidelberg-New York: Springer 1976
Mathé, G.: Immune status and cancer chemotherapy. Cancer Immunol. Immunother. 2, 81 (1977a)
Mathé, G.: Immunopharmacology and immunotherapy of residual disease in cancer patients. In: Medicinal Chemistry, Vol. V. Amsterdam: Elsevier 1977b
Mathé, G., Schneider, M., Schwarzenberg, L.: The time factor in cancer chemotherapy. Europ. J. Cancer 6, 23 (1970)
Mathé, G., Halle-Pannenko, O., Bourut, C.: Effectiveness of murine leukemia chemotherapy according to the immune status. Reconsideration of correlations between chemotherapy, tumor cell killing and survival time. Cancer Immunol. Immunother. 2, 139 (1977)
McVie J. G., Logan, E. C. M., Kay, A. B.: Monocyte function in cancer patients. Europ. J. Cancer 13, 351 (1977)
Mitsuoka, A., Baba, M., Morikawa, S.: Enhancement of delayed hypersensitivity by depletion of suppressor T-cells with cyclophosphamide in mice. Nature (Lond.) 262, 77 (1976)
Nicolin A., Vadlamudi, S., Goldin, A.: Antigenicity of L1210 leukemic sublines induced by drugs. Cancer Res. 32, 653 (1972)
Nicolin, A., Vadlamudi, S., Goldin, A.: Increased immunogenicity of murine lymphatic tumors by parazole-4-carboxamide, 3 (or 5)-amino (NSC-1402; PCA). Cancer Chemother. Rep. 57, 3 (1973)
Nicolin, A., Bini, A., Franco, P., Goldin, A.: Cell-mediated response to mouse leukemic sublime antigenically altered following drug treatment in vivo. Cancer Chemother. Rep. 58, 325 (1974)
Orbach-Arbouys, S., Poupon, M. F.: Active suppression of in vitro reactivity of spleen cells by BCG treatment. Immunology 13 (in press, 1978)
Orbach-Arbouys, S., Castes, M., Berardet, M.: Enhancement of immunological responses by methotrexate pretreatment as a result of an eventual elimination of suppressor cells. In: Experimental Hematology To-day. Heidelberg-Berlin-New York: Springer 1978
Polak, L., Turk, J. L.: Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity. Nature (Lond.) 249, 654 (1974)
Schneider, M.: Effets des chimiothérapies antimitotiques sur une réaction d'hypersensibilité retardée. Rev. franç. Étud. clin. biol. 13, 877 (1968)
Schwartz, R., Dameshek, W.: Drug induced immunological tolerance. Nature (Lond.) 183, 1682 (1959)
Simmler, M. C., Rameau, G., Chou, M. J. Mathé, G.: Monitoring of nonspecific cell-mediated immunity in cancer patients. I. Frequent dissociation between the responses of skin tests to recall antigens and in vitro lymphocyte transformation. Israel J. med. Sci. 12, 472 (1976)
Sy, M. S., Miller, S. D., Claman, H. N.: Immune suppression with supraoptional doses of antigen in contact sensitivity. I. Demonstration of suppressor cells and their sensitivity of cyclophosphamide. J. Immunol. 119, 240 (1977)
Venditti, J. M., Goldin, A.: Drug synergism in antineoplastic chemotherapy. In: Advances in Chemotherapy, Vol. 1, p 397. New York: Academic Press 1964
Weitzman, S. A., Aisenberg, A. C., Siber, G. R., Stossel, T. P., Smith, D. H.: The treatment of Hodgkin's disease (HD) and humoral immunity. Proc. Amer. Ass. Cancer Res. 18, 24 (Abstract 95) (1977)
Winkelstein, A., Mikulla, J. M., Pollack, B. H., Stolzer, B. L.: Altered PHA responses in rheumatoid arthritis patients receiving cyclophosphamide. J. Lab. clin. Med. 80, 506 (1972)
Wright, J. E., Soloway, A. H., Subramanyam, V., Gozzo, J. J.: Mustard haptens for chemoimmunotherapy of cancer. Proc. Amer. Ass. Cancer Res. 18, 233 (Abstract 932) (1977)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mathé, G. Chemotherapy, a double agent in respect of immune functions. Cancer Chemother. Pharmacol. 1, 65–68 (1978). https://doi.org/10.1007/BF00254037
Issue Date:
DOI: https://doi.org/10.1007/BF00254037