Summary
Horseradish peroxidase (HRP) has been injected in visual cortical area 1 (V1, striate cortex) of 33 rabbits (16 received a unilateral injection, 17 bilateral injections) in order to identify its thalamic inputs and to determine their retinotopic organization. This study has shown that when HRP is injected into different portions of V1: 1. Labeled cells are consistently seen in the dorsal lateral geniculate nucleus (LGNd) and are always organized into horizontal columns arranged perpendicularly to the long axis of the LGNd; although the columns are always present in the alpha sector of the LGNd, they extend into the beta sector of this nucleus only occasionally. 2. With a series of injection sites that lie on or near the medial edge of V1 and run rostrocaudally, cell columns shift from ventromedial to dorsolateral within the LGNd. With a series of injection sites that are located along the lateral border of V1 and run from rostral to caudal, columns of labeled cells move from ventral to dorsal along the medial edge of the LGNd. 3. In some of the experiments, with injections in either medial or lateral portions of V1, columns of HRP-labeled cells have also been found within the pulvinar.
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References
Benevento, L.A., Ebner, F.F.: The contribution of the dorsal lateral geniculate nucleus to the total pattern of thalamic terminations in striate cortex of the Virginia opossum. J. comp. Neurol. 143, 243–260 (1971)
Benevento, L.A., Rezak, M.: Extrageniculate projections to layers VI and I of striate cortex (area 17) in the rhesus monkey (Macaca mulatta). Brain Res. 96, 51–55 (1975)
Benevento, L.A., Rezak, M.: The cortical projections of the inferior pulvinar and adjecent lateral pulvinar in the rhesus monkey (Macaca mulatta): an autoradiographic study. Brain Res. 108, 1–24 (1976)
Bodian, D.: The projection of the lateral geniculate body on the cerebral cortex of the opossum, Didelphis virginiana. J. comp. Neurol. 62, 469–494 (1935)
Brouwer, B.: Experimentell-anatomische Untersuchungen über die Projection der Retina auf die primären Opticuszentren. Schweiz. Arch. Neurol. Psychiat. 13, 118–137 (1923)
Clüver, P.F. DE V., Campos-Ortega, J.A.: The cortical projection of the pulvinar in the cat. J. comp. Neurol. 137, 295–308 (1969)
Coleman, J.R., Winer, J.: Projections of the visual thalamus to cortex in opossum demonstrated by horseradish peroxidase. Anat. Rec. 184, 380 (1976)
Colwell, S.A.: Thalamocortical-corticothalamic reciprocity: a combined anterograde-retrograde tracer technique. Brain Res. 92, 443–449 (1975)
Diamond, I.T., Snyder, M., Killackey, H., Jane, J., Hall, W.C.: Thalamo-cortical projections in the tree shrew (Tupaia glis). J. comp. Neurol. 139, 273–306 (1970)
Giolli, R.A., Guthrie, M.D.: Organization of subcortical projections of visual areas I and II in the rabbit. An experimental degeneration study. J. comp. Neurol. 142, 351–376 (1971)
Graham, R.C., Jr., Karnovsky, M.J.: The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique. J. Histochem. Cytochem. 14, 291–302 (1966)
Hall, W.C., Diamond, I.T.: Organization and function of the visual cortex in hedgehog. I. Cortical cytoarchitecture and thalamic retrograde degeneration. Brain Behav. Evol. 1, 181–214 (1968)
Harting, J.K., Diamond, I.T., Hall, W.C.: Anterograde degeneration study of the cortical projections of the lateral geniculate and pulvinar nuclei in the tree shrew (Tupaia glis). J. comp. Neurol. 150, 393–440 (1973)
Hughes, A.: Topographical relationships between the anatomy and physiology of the rabbit visual system. Docum. ophthal. (Den Haag) 30, 33–160 (1971)
Kaas, J.H., Hall, W.C., Diamond, I.T.: Visual cortex of the gray squirrel (Sciurus carolinensis): Architectonic subdivisions and connections from the visual thalamus. J. comp. Neurol. 145, 273–306 (1972)
Karamanlidis, A.N., Giolli, R.A.: Thalamic inputs to the rabbit visual cortex: identification and organization using horseradish peroxidase (HRP). Neuroscience Abstracts 2, 1120 (1976)
Le Gros Clark, W.E., Northfield, D.W. C.: The cortical projection of the pulvinar in the macaque monkey. Brain 60, 126–142 (1937)
Lund, J.S., Lund, R.D., Hendrickson, A.E., Bunt, A.H., Fuchs, A.F.: The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by retrograde transport of horseradish peroxidase. J. comp. Neurol. 164, 287–304 (1975)
Ogren, M., Hendrickson, A.: Pathways between striate cortex and subcortical regions in Macaca mulatta and saimiri sciureus: Evidence for a reciprocal pulvinar connection. Exp. Neurol. 53, 780–800 (1976)
O'Leary, J.L., Bishop, G.H.: Margins of the optically excitable cortex in the rabbit. Arch. Neurol. Psychiat. (Chic.) 40, 482–499 (1938)
Rezak, M., Benevento, L.A.: Topographical projections of the pulvinar to the striate cortex in the macaque monkey. Neuroscience Abstracts 2, 1088 (1976)
Rose, J.E., Malis, L.I.: Geniculo-striate connections in the rabbit. II. Cytoarchitectonic structure of the striate region and of the dorsal lateral geniculate body; organization of the geniculo-striate projections. J. comp. Neurol. 125, 121–140 (1965)
Rose, M.: Cytoarchitektonischer Atlas der Groβhirnrinde des Kaninchens. J. Psychiat. Neurol. (Lpz.) 43, 353–440 (1931)
Rosenquist, A.C., Palmer, L.A., Edwards, S.B., Tusa, R.J.: Thalamic efferents to visual cortical areas in the cat. Neuroscience Abstracts 1, 53 (1975)
Thompson, J.M., Woolsey, C.N., Talbot, S.A.: Visual areas I and II of the cerebral cortex of the rabbit. J. Neurophysiol. 13, 277–288 (1950)
Wilson, M.E., Cragg, B.G.: Projections from the lateral geniculate nucleus in the cat and monkey. J. Anat. (Lond.) 101, 677–692 (1967)
Winfield, D.A., Gatter, K.C., Powell, T.P.S.: Certain connections of the visual cortex of the monkey shown by the use of horseradish Peroxidase. Brain Res. 92, 456–461 (1975)
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A preliminary report of this study (Karamanlidis and Giolli, 1976) has been presented at the sixth annual meeting of the Society for Neurosciences, Toronto, Canada, November 1976
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Karamanlidis, A.N., Giolli, R.A. Thalamic inputs to the rabbit visual cortex: Identification and organization using horseradish peroxidase (HRP). Exp Brain Res 29, 191–199 (1977). https://doi.org/10.1007/BF00237041
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DOI: https://doi.org/10.1007/BF00237041