Skip to main content
Log in

Differential conduction velocities in perforant path fibres in guinea pig

  • Research Note
  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Summary

Conduction velocities (c.vs) of different hippocampal fibre groups have been measured in slices in vitro. In the mossy fibres, Schaffer collaterals and Str. oriens fibres the c.v. varied from 0.36–0.38 m/s; in the alveus c.v. was 1.20 m/s. In the perforant path (p.p.) two groups of c.vs were found: in the medial p.p. the mean (± s.e) c.v. was 0.32 ± 0.02 m/s, whereas in the lateral p.p. it was 1.36 ± 0.14 m/s.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Andersen P, Jansen J, Jr (1961) The local cortical response in the hippocampus of rabbit. Arch Ital Biol 99: 349–368

    Google Scholar 

  • Andersen P, Bliss TVP, Skrede KK (1971) Lamellar organization of hippocampal excitatory pathways. Exp Brain Res 13: 222–238

    Google Scholar 

  • Andersen P, Bland BH, Dubar JD (1973) Organization of the hippocampal outputs. Exp Brain Res 17: 152–168

    Google Scholar 

  • Andersen P, Sundberg SH, Sveen O, Wigström H (1977) Specific long lasting potentiation of synaptic transmission in hippocampus slices. Nature 266: 736–737

    Google Scholar 

  • Gessi T, Sperti L, Volta F (1966) Local response of the hippocampal cortex to direct stimulation in the guinea pig. Arch Sci Biol (Bologne) 50: 20–40

    Google Scholar 

  • Gloor P, Vera CL, Sperti L (1963) Configuration and laminar analysis of the “resting” potential gradient, of the maintransient response to perforant path, fimbrial and mossy fibre volleys and of “spontaneous” activity. Electroencephalogr Clin Neurophysiol 15: 353–378

    Google Scholar 

  • Habets AMMC, Lopes da Silva FH, de Quartel FW (1980) Autoradiography of the olfactory hippocampal pathway in the cat with special reference to the perforant path. Exp Brain Res 38: 257–265

    Google Scholar 

  • Hoesen GW van, Pandya DN (1975) Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. III. Efferent connections. Brain Res 95: 39–59

    Google Scholar 

  • Latsch RH, Cowan WM (1966) Electron microscopic studies of the dentata gyrus of the rat. I. Normal structure with special reference to synaptic organization. J Comp Neurol 128: 359–396

    Google Scholar 

  • Leung LS (1979) Potentials evoked by alvear tract in hippocampal CA1 region of rats. I. Topographical projection, component analysis, and correlation with unit activities. J Neurophysiol 42: 1557–1570

    Google Scholar 

  • Lømo T (1969) Synaptic mechanisms and organization of the dentata area of the hippocampal formation. Thesis, University of Oslo, Norway

    Google Scholar 

  • McNaughton BL, Barnes CA (1979) Opposite effect of paired stimuli on intermediate and distal synapses on dentate granule cells. Neurosci Lett 3: 61

    Google Scholar 

  • Nafstad PHJ (1976) An electron microscope study on termination of the perforant path fibres in the hippocampus and the fascia dentata. Z Zellforsch 76: 532–542

    Google Scholar 

  • Steward O (1976) Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat. J Comp Neurol 167: 285–314

    Google Scholar 

  • Storm-Mathisen J (1977) Localization of transmitter candidates in the brain: The hippocampal formation as a model. Prog Neurobiol 8: 119–181

    Google Scholar 

  • White WF, Nadler JV, Cotman CW (1978) A perfusion chamber for the study of CNS physiology and pharmacology in vitro. Brain Res 152: 591–596

    Google Scholar 

  • Yamamoto C (1972) Activation of hippocampal neurons by mossy fibre stimulation in thin brain sections in vitro. Exp Brain Res 14: 423–435

    Google Scholar 

  • Yamamoto C, Chujo T (1978) Long-term potentiation in thin hippocampal sections studies by intracellular and extracellular recordings. Exp Neurol 58: 242–250

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This work was partly supported by the Foundation for Medical Research (FUNGO), which is subsidized by the Netherlands Organization for the Advancement of Pure Research (ZWO)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tielen, A.M., Lopes da Silva, F.H. & Mollevanger, W.J. Differential conduction velocities in perforant path fibres in guinea pig. Exp Brain Res 42, 231–233 (1981). https://doi.org/10.1007/BF00236913

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00236913

Key words

Navigation