Summary
Podophyllotoxin was produced by cell cultures derived from needles of Callitris drummondii. The needles of this conifer contained 1.56% podophyllotoxin on a dry weight basis, 32% being present in the β-glucosidic form. Trace amounts of desoxypodophyllotoxin and matairesinol were also detected. In dark-grown cell cultures, ca. 0.02 % podophyllotoxin was accumulated, 85–90 % in the β-D-glucosidic form. Moreover, traces of the lignans matairesinol, hinokinin and asarinin were detected. Illumination stimulated the endogenous production of podophyllotoxin-β-D-glucoside; contents of up to 0.11 % could be measured.
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Communicated by W. Barz
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van Uden, W., Pras, N. & Maingré, T.M. The accumulation of podophyllotoxin-β-d-glucoside by cell suspension cultures derived from the conifer Callitris drummondii . Plant Cell Reports 9, 257–260 (1990). https://doi.org/10.1007/BF00232296
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DOI: https://doi.org/10.1007/BF00232296