Abstract
The the aim to assess the clustering of abdominal symptoms in a random population, data from a cohort study of a 70 year old Danish population were analysed. The cohort comprised 1,119 subjects of which 72% participated in a primary study and 91 % of the survivors in a similar study five years later. The following clusters of symptoms were constantly associated. One group constituted abdominal distension, borborygmi, altering stool consistency and number of bowel movements. Pain relieved by bowel movement was associated with this cluster. Nausea and vomiting comprised another cluster. Heartburn/acid regurgitation did not show a consistent association to any other symptoms and may be considered as a cluster of it own. Pain characteristics traditionally related to upper dyspepsia did not specificly relate to any cluster. It is concluded that, in this 70-year-old population abdominal symptoms occur in clusters comparable to clusters in younger populations. The clusters, however, does not totally confirm the traditional concept of Upper Dyspepsia and Irritable Bowel Syndrome.
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Drossman DA, Sandlers RS, McKee DC, Lovitz AJ. Bowel patterns among subjects not seeking health care. Gastroenterol 1982; 83: 529–534.
Talley NJ, Zinsmeister AR, Van Dyke C, Melton LJ. Epidemiology of colonic symptoms and the irritable bowel syndrome. Gastroenterol 1991; 101: 927–934.
Søltoft J, Gudmand-Høyer E, Krag B, Kristensen E, Wulff HR. A double blind trial of the effect of wheat bran on symptoms of the irritable bowel syndrome. Lancet 1976; (i): 270–274.
Khuroo MS, Mahajan R, Zargar SA, Javid G, Munshi S. Prevalence of peptic ulcer in India: an endoscopic and epidemiological study in urban Kashmir. Gut 1989; 30: 930–934.
Jones R, Lydeard S. Prevalence of symptoms of upper dyspepsia in the community. Br Med J 1989; 298: 30–32.
Drossman DA, Thompson WG, Talley NJ, et al. Identification of sub-groups of functional gastrointestinal disorders. Working team report. Gastroenterol Int 1990; 3: 159–172.
Thompson WG, Dotevall G, Drossman DA, Heaton KW, Kruis W. Irritable bowel syndrome: guidelines for diagnosis. Gastroenterol Int 1989; 2: 92–95.
Barbara L, Camilleri M, Corinaldesi R, et al. Definition and investigation of dyspepsia, consensus of an international ad hoc working party. Dig Dis Sci 1989; 34: 1272–1276.
Kay L, Jørgensen T, Jensen KH. The epidemiology of irritable bowel syndrome. Prevalence, incidence, natural history and risk factors. J Int Med 1994; 236: 23–30.
Kay L, Jørgensen T. The epidemiology of upper dyspepsia. Prevalence, incidence, natural history and risk factors. Scand J Gastroenterol 1994; 29: 1–6.
Talley NJ, Piper DW. Comparison of the clinical features and illness behaviour of patients presenting with dyspepsia of unknown cause (essential dys pepsia) and organic disease. Aust NZ J Med 1986; 16: 352–359.
Kay L, Jørgensen T. Abdominal symptom associations in a longitudinal study. Int J Epidemiol 1993; 22: 1093–1100.
Rasmussen BK, Jensen R, Schroll M, Olesen J. Epidemiology of headache in a general population —a prevalence study. J Clin Epidemiol 1991; 44: 1147–1157.
Whittaker J. Grafical models in applied multivariate statistics. New York: John Wiley and Sons, 1990.
Kreiner S. Users guide to DIGRAM, a programme for discrete graphical modeling. Research Report 89/10. Statistical Research Unit, University of Copenhagen, 1989.
Kay L. Prevalence, incidence, and prognosis of gastrointestinal symptoms in a random sample of an elderly population. Age and Ageing 1994; 23: 146–149.
Kruis W, Thieme CH, Weinzier IM, et al. A diagnostic score system for the irritable bowel syndrome: Its value in the exclusion of organic disease. Gastroenterol 1984; 87: 1–7.
Johannessen T, Petersen H, Kleveland PM,et al. The predictive value of history in dyspepsia. Scand J Gastroenterol 1990; 25: 689–697.
Manning AP, Thompson GW, Heaton KW, Morris AF Towards a positive diagnosis of the irritable bowel. Br Med J 1978; 2: 653–654.
Talley NJ, Phillips SF, Melton LJ, et al. Diagnostic value of the Manning criteria in irritable bowel syndrome. Gut 1990; 31: 77–81.
Whitehead WE, Crowell MD, Bosmajian L, et al. Existence of irritable bowel syndrome supported by factor analysis of symptoms in two community samples. Gastroenterology 1990; 98: 336–340.
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Kay, L., Jørgensen, T., Schultz-Larsen, K. et al. Irritable bowel syndrome and upper dyspepsia among the elderly: a study of symptom clusters in a random 70 year old population. Eur J Epidemiol 12, 199–204 (1996). https://doi.org/10.1007/BF00145507
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DOI: https://doi.org/10.1007/BF00145507