Abstract
This chapter entitled “ROS/Redox Signaling and Apoptosis/Necroptosis/Autophagy in Cancer” initially provides a brief account of various programmed cell death (PCD) pathways, e.g., apoptosis, necroptosis, autophagy, and others. Characteristic redox regulatory molecular pathways including specific proteins involved in each PCD pathway have been taken up separately. Each event has been further explained in the context of cancer situations. Specially, PCD resistance, which is considered a hallmark of cancer, has been discussed at the molecular level in various cancerous conditions. Specially, autophagy dual involvement in cancer development has been taken and discussed with the help of ROS and molecular signaling. Further ferroptosis and pyroptosis characteristics have also been introduced.
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Bansal, M.P. (2023). ROS/Redox Signaling and Apoptosis/Necroptosis/Autophagy in Cancer. In: Redox Regulation and Therapeutic Approaches in Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-99-7342-2_4
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DOI: https://doi.org/10.1007/978-981-99-7342-2_4
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