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Applications of Upconversion Nanoparticles in Bio-Imaging

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Upconversion Nanoparticles (UCNPs) for Functional Applications

Part of the book series: Progress in Optical Science and Photonics ((POSP,volume 24))

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Abstract

The last decade has seen rapid advancement in upconversion nanoparticles (UCNPs) for biomedical applications because of their unique characteristics. Technological improvements that have been made for conjugating polymers and dyes, to surface nanoparticles (NPs) have improved their dynamic potential in different domains of the biomedical field. The key advantages of UCNPs, such as their lack of photobleaching, photoblinking, and autofluorescence, not only allow us to build precise, responsive, and multimodal nanoprobes, but also improve therapeutic and diagnostic outcomes. This chapter highlights the unique qualities possessed by the UCNPs and the related processes. Among the diverse applications of UCNPs, including neuromodulation, immunotherapy, drug delivery, photothermal treatments, biosensing, and bioimaging, the main focus of this chapter is bioimaging. Finally, the chapter concludes by providing thoughts on the future prospects and obstacles in the bioimaging domain of UCNP-based nanotechnology research.

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Authors and Affiliations

  1. Department of Physics, National Institute of Technology Srinagar, Jammu and Kashmir, 190006, India

    Irfan Ayoub & Vijay Kumar

  2. Department of Electrical and Computer Engineering, University of Texas at Austin, Austin, TX, 78751, USA

    Rishabh Sehgal

  3. Institute of Forensic Science and Criminology, Panjab University, Chandigarh, 160014, India

    Vishal Sharma

  4. Department of Mechanical Engineering, National Institute of Technology Hamirpur, Himachal Pradesh, 177005, India

    Rakesh Sehgal

  5. Department of Physics, University of the Free State, Bloemfontein, 9300, South Africa

    Hendrik C. Swart & Vijay Kumar

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  1. Irfan Ayoub
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  1. Department of Physics, National Inst of Technology, Srinagar, Srinagar, Jammu and Kashmir, India

    Vijay Kumar

  2. Department of Physics, National Institute of Technology Srinaga, Jammu & Kashmir, India

    Irfan Ayoub

  3. Department of Physics, University of the Free State, Bloemfontein, South Africa

    Hendrik C. Swart

  4. Department of Mechanical Engineering, National Institute of Technology Srinaga, Srinagar, India

    Rakesh Sehgal

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Ayoub, I., Sehgal, R., Sharma, V., Sehgal, R., Swart, H.C., Kumar, V. (2023). Applications of Upconversion Nanoparticles in Bio-Imaging. In: Kumar, V., Ayoub, I., Swart, H.C., Sehgal, R. (eds) Upconversion Nanoparticles (UCNPs) for Functional Applications. Progress in Optical Science and Photonics, vol 24. Springer, Singapore. https://doi.org/10.1007/978-981-99-3913-8_15

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