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Ethnomedicinal Pertinence and Antibacterial Prospective of Himalayan Medicinal Plants of Uttarakhand in India

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Plants for Immunity and Conservation Strategies

Abstract

Uttarakhand is a northern state in India and has a strong traditional medicinal system because of the rich and diverse population of ethnomedicinal plants. Transfer of knowledge to generations on herbal wealth and ancient therapeutic systems has been the tradition among inhabitants of this region. This herbal wealth has been widely utilized as antimicrobial, anticancer, anti-inflammatory, antioxidant, antidiabetic, antifungal, antispasmodic, anthelmintic, antirheumatic, antihepatotoxic, hepatoprotective, analgesic, and immunostimulant for therapeutic treatment strategies.

A recent World Health Organization global report on traditional and complementary medicine 2021–22 confirms the 88% member states have acknowledged their use of traditional and complementary medicine which corresponds to 170 member states. Traditional systems of medicine namely Ayurveda, Unani, Homeopathy, and Siddha are almost completely based on plant-based extracts. Plants which have been studied and investigated pharmacologically and chemically have been helpful in providing active principle in modern medicine and in some cases giving leads for partial or total synthesis of new drugs. Accessibility of modern medical facilities has also played a role in keeping local peoples dependent on traditional methods of using plants as a source for treating ailments. The aim of this study is to review salient reports on traditional, pharmacology, ethnomedicinal, and biological activities of some medicinal plants of Uttarakhand region of India.

Furthermore, medicinal plants are therapeutic agents and raw material for manufacturing traditional and modern medicines. For a better clinical use of Herba Patriniae, it is urgent to establish systematic pharmacology, quality control, and pharmacokinetics validation of these precious heritage plants.

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References

  • Agnihotri S, Wakode S, Ali M (2011) Chemical composition, antimicrobial and topical anti-inflammatory activity of Valeriana Jatamansi Jones. Essential oil. J Essent Oil–Bear Plants 14(4):417–422

    Article  CAS  Google Scholar 

  • Ahmad B, Ismail M, Iqbal Z, Chaudhry MI (2003) Biological activities of geranium wallichianum. Asian J Plant Sci 2:971

    Article  Google Scholar 

  • Akhtar N, Mustafa R (2017) Antibacterial and antioxidant potential of stem bark extract of Bombax ceiba collected locally from South Punjab area of Pakistan. Afr J Tradit Complement Altern Med 14(2):9–15

    Article  PubMed  PubMed Central  Google Scholar 

  • Alam B (2011) Antioxidant, antimicrobial and toxicity studies of the different fractions of fruits of Terminalia belerica Roxb. Glob J Pharmacol 5(1):07–17

    Google Scholar 

  • Al-Asmari AK, Athar MT, Kadasah SG (2017) An updated phytopharmacological review on medicinal plant of Arab region: Apium graveolens Linn. Pharmacogn Rev 11(21):13

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Al-Bayati FA, Sulaiman KD (2008) In vitro antimicrobial activity of Salvadora persica L. extracts against some isolated oral pathogens in Iraq. Turk J Biol 32(1):57–62

    Google Scholar 

  • Al-Mamun M, Jahan N, Chowdhury MH, Jahan R, Nasrin D (2010) Brine shrimp toxicity study of different Bangladeshi medicinal plants. Adv Nat Appl Sci 4(2):163–173

    Google Scholar 

  • Aneja KR, Sharma C, Joshi R (2012) Antimicrobial activity of Terminalia arjuna Wight & Arn.: an ethnomedicinal plant against pathogens causing ear infection. Braz J Otorhinolaryngol 78(1):68–74

    Article  PubMed  Google Scholar 

  • Anesini C, Perez C (1993) Screening of plants used in Argentine folk medicine for antimicrobial activity. J Ethnopharmacol 39(2):119–128

    Article  CAS  PubMed  Google Scholar 

  • Asmawi MZ, Kankaanranta H, Moilanen E, Vapaatalo H (1993) Anti-inflammatory activities of Emblica officinalis Gaertn leaf extracts. J Pharm Pharmacol 45(6):581–584

    Article  CAS  PubMed  Google Scholar 

  • Arora S (2011) Antibacterial, antifungal, antioxidant and phytochemical study on the leaves extract of Grewia optiva. J Pharm Res 4(9):3130–3132

    Google Scholar 

  • Baburao B, Rajyalakshmi G, Venkatesham A, Kiran G, Shyamsunder A, Gangarao B (2009) Anti-inflammatory and antimicrobial activities of methanolic extract of Tribulus terrestris Linn plant. Int J Chem Sci 7(3):1867–1872

    CAS  Google Scholar 

  • Bensehaila S, Ilias F, Saadi F, Zaouadi N (2022) Phenolic compounds and antimicrobial activity of olive (Olea europaea L.) leaves. Asian J Dairy Food Res 41(2):237–241

    Google Scholar 

  • Bhalerao SA, Sharma AS (2014) Ethenomedicinal, phytochemical and pharmacological profile of Ficus religiosa Roxb. Int J Curr Microbiol App Sci 3(11):528–538

    Google Scholar 

  • Bhalodia NR, Nariya PB, Acharya RN, Shukla VJ (2012) In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts. Ayu 33(1):123

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bhatti VP, Vashishtha DP (2008) Indigenous plants in traditional healthcare system in Kedarnath Valley of Western Himalaya

    Google Scholar 

  • Bhavnani SM, Ballow CH (2000) New agents for gram-positive bacteria. Curr Opin Microbiol 3(5):528–534

    Article  CAS  PubMed  Google Scholar 

  • Chanda S, Menpara D, Desai D (2013) Antimicrobial activity of Terminalia bellerica leaf and stem collected from two different sites. Am J Phytomed Clin Ther 1(9):721–733

    Google Scholar 

  • Charu G, Amar PG, Ramesh CU (2008) Antimicrobial activity of some herbal oils against common food-borne pathogens. Afr J Microbiol Res 2(10):258–261

    Google Scholar 

  • Cüneyt Ç, Kevseroglu K, Sağlam B (2004) Physical and physiological dormancy in black henbane (Hyoscyamus Niger L.) seeds. J Plant Biol 47(4):391–395

    Article  Google Scholar 

  • Dagawal J, Ghorpade SD (2011) Antimicrobial activity of an ethnomedicinal plant bidens pilosa L. Int J Pharm Sci Res 2(8):2237–2238

    CAS  Google Scholar 

  • Deka DC, Kumar V, Prasad C, Kumar K, Gogoi BJ, Singh L, Srivastava RB (2013) Oroxylum indicum–a medicinal plant of North East India: an overview of its nutritional, remedial, and prophylactic properties. J Appl Pharm Sci 3(4):S104–S112

    Google Scholar 

  • Dulger B, Goncu BS, Gucin F (2010) Antibacterial activity of the seeds of Hyoscyamus Niger L.(henbane). Asian J Chem 22(9):6879

    CAS  Google Scholar 

  • Dwivedi S (2007) Terminalia Arjuna a useful drug for cardiovascular disorders preventive cardiology group. University College of Medical Sciences, University of Delhi, Delhi

    Google Scholar 

  • Farooquee NA, Majila BS, Kala CP (2004) Indigenous knowledge systems and sustainable management of natural resources in a high altitude society in Kumaun Himalaya, India. J Hum Ecol 16(1):33–42

    Article  Google Scholar 

  • Gangwar M, Goel RK, Nath G (2014) Mallotus philippinensis Muell. Arg (Euphorbiaceae): ethnopharmacology and phytochemistry review. Biomed Res Int 2014:213973

    Article  PubMed  PubMed Central  Google Scholar 

  • Garapati R, Susindran P, Ramesh N (2016) Antimicrobial activity of Curculigo orchioides Gaertn. Callus extract against selected human pathogens. Int J Mod Res Rev 4(7):1184–1187

    Google Scholar 

  • Ghayur A, Kop P (2005) Promoting the cultivation of medicinal plants in Uttaranchal, India. Med Plant Conserv 11:15–19

    Google Scholar 

  • Gülçin I, Küfrevioǧlu Öİ, Oktay M, Büyükokuroǧlu ME (2004) Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). J Ethnopharmacol 90(2–3):205–215

    Article  PubMed  Google Scholar 

  • Gupta A, Dubey M, Parmar M, Mahajan S, Sharma R (2011) Evaluation of antimicrobial activity of Carum carvi (seeds) extract against E. coli and aspergillus Niger. Drug Invent Today 3(9):211–213

    CAS  Google Scholar 

  • Ilango K, Chitra V, Kanimozhi P, Balaji G (2009) Antidiabetic, antioxidant and antibacterial activities of leaf extracts of Adhatoda zeylanica. Medic (Acanthaceae). J Pharm Sci Res 1(2):67

    Google Scholar 

  • Jabeen A, Khan AA, Tabassum A, Mohd M, Mohmad SH (2014) Flaxseed/Tukhm-e-Katan (Linum usitatissimum Linn.): a review. J Pharm Sci Innov 3(5):401–409

    Article  Google Scholar 

  • Jain P, Nimbrana S, Kalia G (2010) Antimicrobial activity and phytochemical analysis of Eucalyptus tereticornis bark and leaf methanolic extracts. Int J Pharm Sci Rev Res 4(2):126–128

    Google Scholar 

  • Janbaz KH, Zaeem Ahsan M, Saqib F, Imran I, Zia-Ul-Haq M, Abid Rashid M, Moga M (2015) Scientific basis for use of Pyrus pashia Buch.-Ham. ex D. Don. fruit in gastrointestinal, respiratory and cardiovascular ailments. PloS One 10(3):e0118605

    Article  PubMed  PubMed Central  Google Scholar 

  • Joshi RK (2011) In vitro antimicrobial activity of the essential oil of Anaphalis contorta hook f. Int J Res Pure Appl Microbiol 1:19–21

    Google Scholar 

  • Kala CP (2000) Status and conservation of rare and endangered medicinal plants in the Indian trans-Himalaya. Biol Conserv 93(3):371–379

    Article  Google Scholar 

  • Kataki MS, Murugamani V, Rajkumari A, Mehra PS, Awasthi D, Yadav RS (2012) Antioxidant, hepatoprotective, and anthelmintic activities of methanol extract of Urtica dioica L. leaves. Pharm Crops 3(1):38–46

    Article  Google Scholar 

  • Krishnaveni V (2017) Investigation of phytochemical and anti-bacterial activity on agave Americana methanolic extract for medical applications. Int J Pharm Bio Sci 8(3):500–505

    CAS  Google Scholar 

  • Kumar S, Navneet, Tiwari MM, Gautam SS (2014) Antimicrobial and phytochemical screening of Olea europaea Linn. Extracts against dental pathogens. Afr J Microbiol Res 8(37):3373–3377

    Article  Google Scholar 

  • Kumar S, Navneet GS, Kumar V (2016) Preliminary phytochemical screening and antimicrobial activity of Salvadora persica Linn extracts against oral pathogens. Fung Genom Biol 6:1–4

    Google Scholar 

  • Kumaraswamy MV, Kavitha HU, Satish S (2008) Antibacterial evaluation and phytochemical analysis of Betula utilis D. Don against some human pathogenic bacteria. World J Agric Sci 4(5):661–664

    Google Scholar 

  • Larsen HO, Olsen CS, Boon TE (2000) The non-timber forest policy process in Nepal: actors, objectives and power. Forest Policy Econ 1(3–4):267–281

    Article  Google Scholar 

  • Lu C, Li Y, Li L, Liang L, Shen Y (2012) Anti-inflammatory activities of fractions from Geranium nepalense and related polyphenols. Drug Discov Ther 6(4):194–197

    CAS  PubMed  Google Scholar 

  • Luximon-Ramma A, Bahorun T, Soobrattee MA, Aruoma OI (2002) Antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of Cassia fistula. J Agric Food Chem 50(18):5042–5047

    Article  CAS  PubMed  Google Scholar 

  • Mishra T, Pal M, Meena S, Datta D, Dixit P, Kumar A, Upreti DK (2016) Composition and in vitro cytotoxic activities of essential oil of Hedychium spicatum from different geographical regions of western Himalaya by principal components analysis. Nat Prod Res 30(10):1224–1227

    Article  CAS  PubMed  Google Scholar 

  • Nael AT, Mohammed AAW (2011) Utility and importance of walnut, Juglans regia Linn: a review. Afr J Microbiol Res 5(32):5796–5805

    Google Scholar 

  • Negi BS, Dave BP (2010) In vitro antimicrobial activity of Acacia catechu and its phytochemical analysis. Indian J Microbiol 50(4):369374

    Article  Google Scholar 

  • Negi VS, Maikhuri RK, Rawat LS (2011) Non-timber forest products (NTFPs): a viable option for biodiversity conservation and livelihood enhancement in central Himalaya. Biodivers Conserv 20(3):545–559

    Article  Google Scholar 

  • Negi JS, Bisht VK, Bhandari AK, Sundriyal RC (2012) Effects of extraction solvents on concentration of valerenic acid and antioxidant property of Valeriana jatamansi jones. Int J Pharm Bio Sci 3(4):28–35

    Google Scholar 

  • Okwu DE, Josiah C (2006) Evaluation of the chemical composition of two Nigerian medicinal plants. Afr J Biotechnol 5(4):357–361

    CAS  Google Scholar 

  • Olsen CS (2005) Valuation of commercial central Himalayan medicinal plants. Ambio 34(8):607–610

    Article  PubMed  Google Scholar 

  • Othman L, Sleiman A, Abdel-Massih RM (2019) Antimicrobial activity of polyphenols and alkaloids in middle eastern plants. Front Microbiol 10:911

    Article  PubMed  PubMed Central  Google Scholar 

  • Pandey MK, Singh GN, Sharma RK, Lata S (2011) Antibacterial activity of Eclipta alba (L.) Hassk. J Appl Pharm Sci Issue:104–107

    Google Scholar 

  • Patel KP, Patel AM, Chaute SB (2009) Antimicrobial activity of various extract from the leaves of Taxus baccata Linn (Taxaceae). Pharmacology 2:217–224

    Google Scholar 

  • Patel JJ, Acharya SR, Acharya NS (2014) Clerodendrum serratum (L.) moon.–a review on traditional uses, phytochemistry and pharmacological activities. J Ethnopharmacol 154(2):268–285

    Article  CAS  PubMed  Google Scholar 

  • Priya K, Ganjewala D (2007) Antibacterial activities and phytochemical analysis of different plant parts of Nyctanthes arbor-tristis (Linn.). Res J Phytochem 1(2):61–67

    Article  Google Scholar 

  • Puri A, Srivastava AK, Singhal B, Mishra SK, Srivastava S, Lakshmi V (2011) Antidyslipidemic and antioxidant activity of Pinus roxburghii needles. Med Chem Res 20(9):1589–1593

    Article  CAS  Google Scholar 

  • Purohit A, Maikhuri RK, Rao KS, Nautiyal S (2001) Impact of bark removal on survival of Taxus baccata L.(Himalayan yew) in Nanda Devi biosphere reserve, Garhwal Himalaya, India. Curr Sci 1:586–590

    Google Scholar 

  • Qadir M, Shah WA, Banday JA (2014) GC-MS analysis, antibacterial, antioxidant and anticancer activity of essential oil of Pinus roxburghii from Kashmir, India. Int J Res Pharm Chem 4(1):228–232

    Google Scholar 

  • Rahman MM, Alam MJ, Sharmin SA, Rahman MM, Rahman A, Alam MF (2009) In vitro antibacterial activity of Argemone mexicana (Papaveraceae). CMU J Nat Sci 8:77–84

    Google Scholar 

  • Ramakrishnaiah G, Hariprasad T (2013) In vitro antimicrobial activity of leaves and bark extracts of Ficus religiosa (Linn.). Indian J Pharm Biol Res 1(01):38–43

    Article  Google Scholar 

  • Rameshwar V, Kishor D, Tushar G, Siddharth G, Sudarshan G (2014) A pharmacognostic and pharmacological overview on Bombax ceiba. Sch Acad J Pharm 3(2):100–107

    Google Scholar 

  • Ramsewak RS, Nair MG, Strasburg GM, DeWitt DL, Nitiss JL (1999) Biologically active carbazole alkaloids from Murraya koenigii. J Agric Food Chem 47(2):444–447

    Article  CAS  PubMed  Google Scholar 

  • Rana S, Prakash V, Sagar A (2016) Antibacterial activity of Mallotus philippensis fruit extract. J Med Plants Stud 4(3):104–106

    Google Scholar 

  • Rani DN, Abraham TE (2006) Kinetic study of a purified anionic peroxidase isolated from Eupatorium odoratum and its novel application as time temperature indicator for food materials. J Food Eng 77(3):594–600

    Article  CAS  Google Scholar 

  • Rani S, Rahman K, Younis M, Basar SN (2015) Dhawa (Woodfordia fruticosa (L.) Kurz.): a versatile medicinal plant. Int J Pharm Sci Drug Res 7(4):315–320

    CAS  Google Scholar 

  • Rashel Kabir S, Hossen A, Abu Zubair M, Jahangir Alom M, Islam F, Hossain A, Kimura Y (2011) A new lectin from the tuberous rhizome of Kaempferia rotunda: isolation, characterization, antibacterial and antiproliferative activities. Protein Pept Lett 18(11):1140–1149

    Article  Google Scholar 

  • Rather AM, Nawchoo IA, Ganie AH, Singh H, Dutt B, Wani AA (2012) Bioactive compounds & medicinal properties of Valeriana jatamansi Jones-a review. Life Sci J 9(2):847–850

    Google Scholar 

  • Raturi R, Sati SC, Singh H, Sati MD, Badoni PP (2012) Phytochemical examination of Anaphalis busua leaves. In: Chemistry of phytopotentials: health, energy and environmental perspectives. Springer, Berlin, Heidelberg, pp 105–106

    Chapter  Google Scholar 

  • Rawat S, Jugran A, Giri L, Bhatt ID, Rawal RS (2011) Assessment of antioxidant properties in fruits of Myrica esculenta: A popular wild edible species in Indian Himalayan region. Evid Based Complement Alternat Med 2011:2011

    Article  Google Scholar 

  • Ross IA (2005) Medicinal plants of the world, volume 3: chemical constituents, traditional and modern medicinal uses. Humana Press Incorporated, Louisville, KY

    Google Scholar 

  • Sahu N, Arya KR (2017) Ethnobotanical and ethnopharmacological activities of Artemisia nilagirica, Lyonia ovalifolia, Sarcococca saligna and Taraxacum officinale. Int J Pharm Sci Res 8(11):4818–4825

    CAS  Google Scholar 

  • Saikot FK, Khan A, Hasan MF (2012) Antimicrobial and cytotoxic activities of Abroma augusta Lnn. Leaves extract. Asian Pac J Trop Biomed 2(3):S1418–S1422

    Article  Google Scholar 

  • Saini R, Dangwal K, Singh H, Garg V (2014) Antioxidant and antiproliferative activities of phenolics isolated from fruits of Himalayan yellow raspberry (Rubus ellipticus). J Food Sci Technol 51(11):3369–3375

    Article  CAS  PubMed  Google Scholar 

  • Sanjay K, Murli MT, Shiv SG (2014) Antimicrobial and phytochemical screening of Olea europaea Linn. Extracts against dental pathogens. Afr J Microbiol Res 8(37):3373–3377

    Article  Google Scholar 

  • Sarla S, Subhash C (2012) Preliminary phytochemical evaluation of Garhwal Himalaya wild edible fruit Pyracantha crenulata. J Pharm Res 5(6):3434–3436

    Google Scholar 

  • Sati SC, Sati N, Sati OP (2011) Chemical investigation and screening of antimicrobial activity of stem bark of Qurecus leucotrichophora. Int J Pharm Pharm Sci 3:89–91

    CAS  Google Scholar 

  • Sayeed A, Madhukar G, Maksood A, Mhaveer S, Athar MT, Ansari SH (2009) A phyto-pharmacological overview on Adhatoda zeylanica medic. Syn. A. vasica (Linn.) Nees. Nat Prod Radiance 8(5):549–554

    Google Scholar 

  • Shahavi VM, Desai SK (2008) Anti-inflammatory activity of Butea monosperma flowers. Fitoterapia 79(2):82–85

    Article  CAS  PubMed  Google Scholar 

  • Shaheen S, Bibi M, Hussain H, Iqbal Saira I, Safdar Laraib S (2017) A review on geranium wallichianum D-Don ex-sweet: an endangered medicinal herb from Himalaya region. Med Aromat Plants 6(288):1000288

    Google Scholar 

  • Shankar GS, Navneet M, Sanjay K, Prabhat M (2012) Screening of antibacterial activity of Nepeta ciliaris Benth. Against respiratory tract pathogens. Kathmandu Univ J Sci Eng Technol 8(1):100–103

    Article  Google Scholar 

  • Siddiqui BS, Usmani SB, Begum S, Siddiqui S (1993) Steroidal alkaloids and an androstane derivative from the bark of Holarrhena pubescens. Phytochemistry 33(4):925–928

    Article  CAS  Google Scholar 

  • Siddiqui MF, Ahmed M, Wahab M, Khan N, Khan MU, Nazim K, Hussain SS (2009) Phytosociology of Pinus roxburghii Sargent (chir pine) in lesser Himalayan and Hindu Kush range of Pakistan. Pak J Bot 41(5):2357–2369

    Google Scholar 

  • Singh A, Dhariwal SN (2018) Traditional uses, antimicrobial potential, pharmacological properties and phytochemistry of Viola odorata: a mini review. Int J Phytopharm 7:103–105

    Article  Google Scholar 

  • Singh SS, Pandey SC, Srivastava S, Gupta VS, Patro B (2003) Chemistry and medicinal properties of Tinospora cordifolia (Guduchi). Indian J Pharm 35(2):83

    CAS  Google Scholar 

  • Singh MK, Khare G, Iyer SK, Sharwan G, Tripathi DK (2012) Clerodendrum serratum: a clinical approach. J Appl Pharm Sci Issue:11–15

    Google Scholar 

  • Singh BR, Agrawal R, Sinha DK, Vinodh OR, Vadhana P, Bhardwaj M, Singh S (2015) Antimicrobial activity in aqueous and methanolic leaf extract of Eupatorium odoratum against bacteria of clinical and nonclinical origin. J Adv Clin Pharmacol 2(2):50–59

    Article  Google Scholar 

  • Sisay M, Bussa N, Gashaw T, Mengistu G (2019) Investigating in vitro antibacterial activities of medicinal plants having folkloric repute in Ethiopian traditional medicine. J Evid Based Integr Med 24:2515690X19886276

    Article  PubMed  PubMed Central  Google Scholar 

  • Srivastava N, Sharma V, Saraf K, Dobriyal AK, Kamal B, Jadon VS (2011) In vitro antimicrobial activity of aerial parts extracts of Aconitum heterophyllum wall. Ex Royle

    Google Scholar 

  • Sultana A, Hossain MJ, Kuddus MR, Rashid MA, Zahan MS, Mitra S, Naina Mohamed I (2022) Ethnobotanical uses, Phytochemistry, toxicology, and pharmacological properties of Euphorbia neriifolia Linn. Against infectious diseases: a comprehensive review. Molecules 27(14):4374

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Susindran P, Ramesh N (2014) Anti-diabetic effect of Curculigo orchioides Gaertn extracts in alloxan induced diabetic rats. J Pharm Res 8(7):942–947

    Google Scholar 

  • Tachibana Y, Kikuzaki H, Lajis NH, Nakatani N (2001) Antioxidative activity of carbazoles from Murraya koenigii leaves. J Agric Food Chem 49(11):5589–5594

    Article  CAS  PubMed  Google Scholar 

  • Thakur SC, Thakur SS, Chaube SK, Singh SP (2005) An etheral extract of Kamala (Mallotus philippinensis (moll. Arg) lam.) seed induce adverse effects on reproductive parameters of female rats. Reprod Toxicol 20(1):149–156

    Article  CAS  PubMed  Google Scholar 

  • Theng KB, Korpenwar AN (2012) Pharmacognostic, phytochemical and physicochemical investigation of Pueraria tuberosa (Roxb. Ex Willd.) DC. Tuber

    Google Scholar 

  • Tyagi S, Chirag P, Dhruv M, Ishita M, Gupta AK, Usman M, Maheshwari R (2013) Medical benefits of Apium graveolens (celery herb). J Drug Discov Ther 1(5):36–38

    Google Scholar 

  • Udoh DI, Asamudo NU, Bala DN, Enwongo O (2012) Inhibitory effect of varying concentrations of leaves’ extracts of Centella Asiatica(Gotu Kola) on some microorganisms of medical importance. Int J Chem Environ Pharm Res 3(2):142–148

    Google Scholar 

  • Vashisht S, Singh MP, Chawla V (2016) In-vitro antioxidant and antibacterial activity of methanolic extract of Shorea robusta Gaertn. F resin. Int J Pharm Phytopharmacological Res 6(4):68–71

    Article  CAS  Google Scholar 

  • Wagner H, Geyer B, Kiso Y, Hikino H, Rao GS (1986) Coumestans as the main active principles of the liver drugs Eclipta alba and Wedelia calendulacea. Planta Med 52(05):370–374

    Article  Google Scholar 

  • Wollenweber E, Fritz H, Henrich B, Jakupovic J, Schilling G, Roitman JN (1993) Rare flavonoid aglycones from Anaphalis margaritacea and two Gnaphalium species. Z Naturforsch C 48(5–6):420–424

    Article  CAS  Google Scholar 

  • Yadav RP, Patel AK, Jagannadham MV (2012) Neriifolin S, a dimeric serine protease from Euphorbia neriifolia Linn.: purification and biochemical characterisation. Food Chem 132(3):1296–1304

    Article  CAS  PubMed  Google Scholar 

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Mehra, S., Sharma, V.K., Tygai, C., Tomar, L.K. (2023). Ethnomedicinal Pertinence and Antibacterial Prospective of Himalayan Medicinal Plants of Uttarakhand in India. In: Mishra, M.K., Kumari, N. (eds) Plants for Immunity and Conservation Strategies. Springer, Singapore. https://doi.org/10.1007/978-981-99-2824-8_15

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