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FCFNet: A Network Fusing Color Features and Focal Loss for Diabetic Foot Ulcer Image Classification

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Neural Information Processing (ICONIP 2022)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1793))

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Abstract

Diabetic foot ulcers (DFU) are one of the most common and severe complications of diabetes. More than one million diabetics face amputation due to failure to recognize and treat DFU properly every year, and it is very important to early recognize the condition of DFU. As deep learning has achieved outstanding results in computer vision tasks, some deep learning methods have been used for diabetic foot ulcer image classification. However, these models do not pay attention to the learning of color information in images and may not effectively learn the characteristics of hard examples, which are difficult to recognize by models trained by common loss functions. In addition, they may be time-consuming or not suitable for small datasets. According to DFU medical classification systems, the presence of infection and ischemia has important clinical implications for DFU assessment. In our work, based on the characteristics of gangrene and wound, which are significantly different from the surrounding skin and the background, we use the K-Means algorithm to segment the features and further build the classification model with the segmentation module. Next, we use focal loss to train EfficientNet B3, which can make this model better learn the characteristics of hard examples. We finally use the two powerful networks for testing. The experimental results demonstrate that compared with other excellent classification models, our model has better performance with a macro-average F1-score of 0.6334, which has great potential in medical assisted diagnosis.

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References

  1. Aguiree, F., et al.: IDF diabetes atlas (2013)

    Google Scholar 

  2. Albers, M., Fratezi, A.C., De Luccia, N.: Assessment of quality of life of patients with severe ischemia as a result of infrainguinal arterial occlusive disease. J. Vasc. Surg. 16(1), 54–59 (1992)

    Article  Google Scholar 

  3. Alzubaidi, L., Fadhel, M.A., Oleiwi, S.R., Al-Shamma, O., Zhang, J.: DFU_QUTNet: diabetic foot ulcer classification using novel deep convolutional neural network. Multimedia Tools Appl. 79(21), 15655–15677 (2020)

    Article  Google Scholar 

  4. Armstrong, D.G., Boulton, A.J., Bus, S.A.: Diabetic foot ulcers and their recurrence. New England J. Med. 376(24), 2367–2375 (2017)

    Article  Google Scholar 

  5. Armstrong, D.G., Lavery, L.A., Harkless, L.B.: Validation of a diabetic wound classification system: the contribution of depth, infection, and ischemia to risk of amputation. Diabetes Care 21(5), 855–859 (1998)

    Article  Google Scholar 

  6. Bloch, L., Brüngel, R., Friedrich, C.M.: Boosting efficientnets ensemble performance via pseudo-labels and synthetic images by pix2pixHD for infection and ischaemia classification in diabetic foot ulcers. arXiv preprint arXiv:2112.00065 (2021). https://doi.org/10.1007/978-3-030-94907-5_3

  7. Cassidy, B., et al.: Diabetic foot ulcer grand challenge 2021: evaluation and summary. arXiv preprint arXiv:2111.10376 (2021). https://doi.org/10.1007/978-3-030-94907-5_7

  8. Cassidy, B., et al.: DFUC 2020: analysis towards diabetic foot ulcer detection. arXiv abs/2004.11853 (2021)

    Google Scholar 

  9. Cassidy, B., et al.: The DFUC 2020 dataset: analysis towards diabetic foot ulcer detection. TouchREV. Endocrinol. 17(1), 5–11 (2021)

    Google Scholar 

  10. Deng, J., Dong, W., Socher, R., Li, L.J., Li, K., Fei-Fei, L.: ImageNet: a large-scale hierarchical image database. In: 2009 IEEE Conference on Computer Vision and Pattern Recognition, pp. 248–255. IEEE (2009)

    Google Scholar 

  11. Dosovitskiy, A., et al.: An image is worth 16\(\,\times \,\)16 words: Transformers for image recognition at scale. arXiv preprint arXiv:2010.11929 (2020)

  12. Foret, P., Kleiner, A., Mobahi, H., Neyshabur, B.: Sharpness-aware minimization for efficiently improving generalization. arXiv preprint arXiv:2010.01412 (2020)

  13. Galdran, A., Carneiro, G., Ballester, M.A.G.: Convolutional nets versus vision transformers for diabetic foot ulcer classification. arXiv preprint arXiv:2111.06894 (2021)

  14. Goyal, M., Reeves, N.D., Davison, A.K., Rajbhandari, S., Spragg, J., Yap, M.H.: DFUNet: convolutional neural networks for diabetic foot ulcer classification. IEEE Trans. Emerg. Top. Comput. Intell. 4(5), 728–739 (2018)

    Article  Google Scholar 

  15. Goyal, M., Reeves, N.D., Rajbhandari, S., Ahmad, N., Wang, C., Yap, M.H.: Recognition of ischaemia and infection in diabetic foot ulcers: dataset and techniques. Comput. Biol. Med. 117, 103616 (2020)

    Article  Google Scholar 

  16. Goyal, M., Reeves, N.D., Rajbhandari, S., Yap, M.H.: Robust methods for real-time diabetic foot ulcer detection and localization on mobile devices. IEEE J. Biomed. Health Inform. 23(4), 1730–1741 (2018)

    Article  Google Scholar 

  17. Goyal, M., Yap, M.H., Reeves, N.D., Rajbhandari, S., Spragg, J.: Fully convolutional networks for diabetic foot ulcer segmentation. In: 2017 IEEE International Conference on Systems, Man, and Cybernetics (SMC), pp. 618–623. IEEE (2017)

    Google Scholar 

  18. He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  19. Korpelevich, G.M.: The extragradient method for finding saddle points and other problems. Matecon 12, 747–756 (1976)

    MathSciNet  MATH  Google Scholar 

  20. Lavery, L.A., Armstrong, D.G., Wunderlich, R.P., Tredwell, J., Boulton, A.J.: Diabetic foot syndrome: evaluating the prevalence and incidence of foot pathology in Mexican Americans and non-Hispanic whites from a diabetes disease management cohort. Diabetes Care 26(5), 1435–1438 (2003)

    Article  Google Scholar 

  21. Lin, T.Y., Goyal, P., Girshick, R., He, K., Dollár, P.: Focal loss for dense object detection. In: Proceedings of the IEEE International Conference on Computer Vision, pp. 2980–2988 (2017)

    Google Scholar 

  22. Lipsky, B.A., et al.: 2012 infectious diseases society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin. Infect. Dis. 54(12), e132–e173 (2012)

    Article  Google Scholar 

  23. Liu, Z., et al.: Swin transformer: hierarchical vision transformer using shifted windows. arXiv preprint arXiv:2103.14030 (2021)

  24. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431–3440 (2015)

    Google Scholar 

  25. Mills Sr, J.L., et al.: Society for Vascular Surgery Lower Extremity Guidelines Committee. The society for vascular surgery lower extremity threatened limb classification system: risk stratification based on wound, ischemia, and foot infection (WIfI). J. Vasc. Surg. 59(1), 220–234 (2014)

    Google Scholar 

  26. Patel, S., Patel, R., Desai, D.: Diabetic foot ulcer wound tissue detection and classification. In: 2017 International Conference on Innovations in Information, Embedded and Communication Systems (ICIIECS). pp. 1–5. IEEE (2017)

    Google Scholar 

  27. Prompers, L., et al.: High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study. Diabetologia 50(1), 18–25 (2007)

    Google Scholar 

  28. Rania, N., Douzi, H., Yves, L., Sylvie, T.: Semantic segmentation of diabetic foot ulcer images: dealing with small dataset in DL approaches. In: El Moataz, A., Mammass, D., Mansouri, A., Nouboud, F. (eds.) ICISP 2020. LNCS, vol. 12119, pp. 162–169. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-51935-3_17

    Chapter  Google Scholar 

  29. Ren, S., He, K., Girshick, R., Sun, J.: Faster R-CNN: towards real-time object detection with region proposal networks. IEEE Trans. Pattern Anal. Mach. Intell. 39(6), 1137–1149 (2016)

    Article  Google Scholar 

  30. Roglic, G., et al.: WHO Global report on diabetes: a summary. Int. J. Noncommun. Dis. 1(1), 3 (2016)

    Article  Google Scholar 

  31. Saeedi, P., et al.: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the international diabetes federation diabetes atlas. Diabetes Res. Clin. Pract. 157, 107843 (2019)

    Article  Google Scholar 

  32. Tan, M., Le, Q.: EfficientNet: rethinking model scaling for convolutional neural networks. In: International Conference on Machine Learning, pp. 6105–6114. PMLR (2019)

    Google Scholar 

  33. Vardasca, R., Magalhaes, C., Seixas, A., Carvalho, R., Mendes, J.: Diabetic foot monitoring using dynamic thermography and AI classifiers. In: Proceedings of the 3rd Quantitative InfraRed Thermography Asia Conference (QIRT Asia 2019), Tokyo, Japan. pp. 1–5 (2019)

    Google Scholar 

  34. Xie, S., Girshick, R., Dollár, P., Tu, Z., He, K.: Aggregated residual transformations for deep neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 1492–1500 (2017)

    Google Scholar 

  35. Xu, Y., Han, K., Zhou, Y., Wu, J., Xie, X., Xiang, W.: Classification of diabetic foot ulcers using class knowledge banks. Front. Bioeng. Biotechnol. 9 (2021)

    Google Scholar 

  36. Yap, M.H., Cassidy, B., Pappachan, J.M., O’Shea, C., Gillespie, D., Reeves, N.: Analysis towards classification of infection and ischaemia of diabetic foot ulcers. arXiv preprint arXiv:2104.03068 (2021)

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Acknowledgements

We have obtained the authorization of the organizers of DFUC 2021 for research, who have received approval from the UK National Health Service (NHS) Research Ethics Committee (REC). The computation is supported by the School of Computer Engineering and Science of Shanghai University. This work is supported by the NSFCs of China (No. 61902234).

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Correspondence to Chuantao Xie .

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Xie, C. (2023). FCFNet: A Network Fusing Color Features and Focal Loss for Diabetic Foot Ulcer Image Classification. In: Tanveer, M., Agarwal, S., Ozawa, S., Ekbal, A., Jatowt, A. (eds) Neural Information Processing. ICONIP 2022. Communications in Computer and Information Science, vol 1793. Springer, Singapore. https://doi.org/10.1007/978-981-99-1645-0_36

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  • DOI: https://doi.org/10.1007/978-981-99-1645-0_36

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