Abstract
A 15-year-old girl presented to the dental OPD with maxillary swelling (Fig. 1). A biopsy was done from the maxillary swelling was suggestive of brown tumor. Hence the patient was referred to the Endocrine surgery department. Biochemical evaluation showed raised serum calcium, low phosphorus, and high intact parathyroid hormone. A review of plain radiographs revealed multiple fractures with diffuse osteopenia. Brown tumors were also observed at multiple sites (shaft of the left femur, and the shaft of the left tibia). These findings were consistent with osteitis fibrosa cystica. Localizing investigation pointed to right superior enlarged parathyroid gland. Focused parathyroidectomy was done with 50% drop in iPTH level at 10 min (Miami’s criteria). Postoperatively patient was started on prophylactic calcium infusion and was continued for 5 days along with oral calcium and active vitamin D (Figs. 2 and 3).
Roma Pradhan is the lead author of this chapter.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Panagopoulos A, Tatani I, Kourea HP, Kokkalis ZT, Panagopoulos K, Megas P. Osteolytic lesions (brown tumors) of primary hyperparathyroidism misdiagnosed as multifocal giant cell tumor of the distal ulna and radius: a case report. J Med Case Rep. 2018;12(1):176.
Rodríguez-Gutiérrez R, Hinojosa-Amaya JM. Brown tumors: severe osteitis fibrosa cystica. Mayo Clin Proc. 2015;90(5):699–700.
Nikodimopoulou M, Liakos S. Secondary hyperparathyroidism and target organs in chronic kidney disease. Hippokratia. 2011;15(Suppl 1):33–8.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Agarwal, A., Fernando, R., Parameswaran, R., Mishra, A., Pradhan, R. (2023). PHPT Presenting as Osteitis Fibrosa Cystica. In: Case Studies in Thyroid and Parathyroid Tumors. Springer, Singapore. https://doi.org/10.1007/978-981-99-0938-4_1
Download citation
DOI: https://doi.org/10.1007/978-981-99-0938-4_1
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-99-0937-7
Online ISBN: 978-981-99-0938-4
eBook Packages: MedicineMedicine (R0)