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Bone Health

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  • First Online:
Encyclopedia of Feeding and Eating Disorders

Synonyms

Bone density; Bone mineral density; Low bone mineral density; Osteoporosis

Definition

Bone health is as a public health issue. Maintaining a healthy skeleton is an important andcomplex process. Many things can interfere with the development of healthy bones. For instance, genetic abnormalities, nutritional deficiencies and hormonal disorders can affect the skeleton. In addition, lack of exercise, immobilization, alcohol use, certain medications and smoking can also have negative effects on bone mass and strength. Many disorders can also affect the skeleton. Anorexia nervosa, an eating disorder that primarily affects adolescent girls and young women, associated with low bone mineral density and osteoporosis in adults. Anorexia nervosa is characterized by persistent restriction of energy intake leading to low body weight; an intense fear of gaining weight or of becoming fat or persistent behavior that impedes weight gain; and disordered body image or lack of recognition of the...

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References and Further Reading

  • Anastasia, D., Lyritis, G. P., & Tournis, S. (2014). Bone disease in anorexia nervosa. Hormones, 13(1), 38–56.

    Google Scholar 

  • Divasta, A. D., Feldman, H. A., Giancaterino, C., Rosen, C. J., Leboff, M. S., & Gordon, C. M. (2012). The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa. Metabolism, 61(7), 1010–1020. Epub 2012/01/20.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • DiVasta, A. D., Feldman, H. A., Beck, T. J., LeBoff, M. S., & Gordon, C. M. (2014). Does hormone replacement normalize bone geometry in adolescents with anorexia nervosa? Journal of Bone and Mineral Research, 29(1), 151–157. Epub 2013/06/08.

    Article  CAS  PubMed  Google Scholar 

  • Fazeli, P. K., & Klibanski, A. (2014). Anorexia nervosa and bone metabolism. Bone, 66, 39–45. Epub 2014/06/03.

    Article  CAS  PubMed  Google Scholar 

  • Fazeli, P. K., Lawson, E. A., Prabhakaran, R., Miller, K. K., Donoho, D. A., Clemmons, D. R., et al. (2010). Effects of recombinant human growth hormone in anorexia nervosa: A randomized, placebo-controlled study. Journal of Clinical Endocrinology and Metabolism, 95(11), 4889–4897. Epub 2010/07/30.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Golden, N. H., Lanzkowsky, L., Schebendach, J., Palestro, C. J., Jacobson, M. S., & Shenker, I. R. (2002). The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa. Journal of Pediatric and Adolescent Gynecology, 15(3), 135–143.

    Article  PubMed  Google Scholar 

  • Golden, N. H., Iglesias, E. A., Jacobson, M. S., Carey, D., Meyer, W., Schebendach, J., et al. (2005). Alendronate for the treatment of osteopenia in anorexia nervosa: A randomized, double-blind, placebo-controlled trial. Journal of Clinical Endocrinology and Metabolism, 90(6), 3179–3185. Epub 2005/03/24.

    Article  CAS  PubMed  Google Scholar 

  • Gordon, C. M., Grace, E., Emans, S. J., Feldman, H. A., Goodman, E., Becker, K. A., et al. (2002). Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: A randomized trial. Journal of Clinical Endocrinology and Metabolism, 87(11), 4935–4941. Epub 2002/11/05.

    Article  CAS  PubMed  Google Scholar 

  • Gordon, C. M., Leonard, M. B., & Zemel, B. S. (2014). 2013 pediatric position development conference: Executive summary and reflections. Journal of Clinical Densitometry, 17(2), 219–224. Epub 2014/03/25.

    Article  PubMed  Google Scholar 

  • Grinspoon, S., Thomas, L., Miller, K., Herzog, D., & Klibanski, A. (2002). Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. Journal of Clinical Endocrinology and Metabolism, 87(6), 2883–2891.

    Article  CAS  PubMed  Google Scholar 

  • Katzman, D. K., & Misra, M. (2013). Bone health in adolescent females with anorexia nervosa: What is a clinician to do? International Journal of Eating Disorders, 46(5), 456–460. Epub 2013/05/10.

    Article  PubMed  Google Scholar 

  • Klibanski, A., Biller, B. M., Schoenfeld, D. A., Herzog, D. B., & Saxe, V. C. (1995). The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. Journal of Clinical Endocrinology and Metabolism, 80(3), 898–904. Epub 1995/03/01.

    CAS  PubMed  Google Scholar 

  • Lewiecki, E. M., Gordon, C. M., Baim, S., Leonard, M. B., Bishop, N. J., Bianchi, M. L., et al. (2008). International society for clinical densitometry 2007 adult and pediatric official positions. Bone, 43(6), 1115–1121. Epub 2008/09/17.

    Article  PubMed  Google Scholar 

  • Miller, K. K., Meenaghan, E., Lawson, E. A., Misra, M., Gleysteen, S., Schoenfeld, D., et al. (2011). Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: A randomized, placebo-controlled study. Journal of Clinical Endocrinology and Metabolism, 96(7), 2081–2088. Epub 2011/04/29.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Misra, M., & Klibanski, A. (2014a). Anorexia nervosa and bone. Journal of Endocrinology, 221(3), R163–R176. Epub 2014/06/06.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Misra, M., & Klibanski, A. (2014b). Endocrine consequences of anorexia nervosa. The Lancet Diabetes and Endocrinology, 2(7), 581–592. Epub 2014/04/16.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Misra, M., Le Clair, M., Mendes, N., Miller, K. K., Lawson, E., Meenaghan, E., et al. (2010). Use of SSRIs may impact bone density in adolescent and young women with anorexia nervosa. CNS Spectrums, 15(9), 579–586. Epub 2010/09/01.

    Article  PubMed  PubMed Central  Google Scholar 

  • Misra, M., Katzman, D., Miller, K. K., Mendes, N., Snelgrove, D., Russell, M., et al. (2011). Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa. Journal of Bone and Mineral Research, 26(10), 2430–2438. Epub 2011/06/24.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sienkiewicz, E., Magkos, F., Aronis, K. N., Brinkoetter, M., Chamberland, J. P., Chou, S., et al. (2011). Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women. Metabolism, 60(9), 1211–1221. Epub 2011/07/12.

    Article  CAS  PubMed  Google Scholar 

  • Sim, L. A., McGovern, L., Elamin, M. B., Swiglo, B. A., Erwin, P. J., & Montori, V. M. (2010). Effect on bone health of estrogen preparations in premenopausal women with anorexia nervosa: A systematic review and meta-analyses. International Journal of Eating Disorders, 43(3), 218–225. Epub 2009/04/08.

    PubMed  Google Scholar 

  • Sonneville, K. R., Gordon, C. M., Kocher, M. S., Pierce, L. M., Ramappa, A., & Field, A. E. (2012). Vitamin D, calcium, and dairy intakes and stress fractures among female adolescents. Archives of Pediatrics and Adolescent Medicine, 166(7), 595–600. Epub 2012/03/07.

    Article  PubMed  PubMed Central  Google Scholar 

  • Strokosch, G. R., Friedman, A. J., Wu, S. C., & Kamin, M. (2006). Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: A double-blind, placebo-controlled study. Journal of Adolescent Health, 39(6), 819–827.

    Article  PubMed  Google Scholar 

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Correspondence to Debra K. Katzman .

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© 2017 Springer Nature Singapore Pte Ltd.

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Katzman, D.K., Gordon, C.M. (2017). Bone Health. In: Wade, T. (eds) Encyclopedia of Feeding and Eating Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-287-104-6_70

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  • DOI: https://doi.org/10.1007/978-981-287-104-6_70

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-287-103-9

  • Online ISBN: 978-981-287-104-6

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