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Adjuvant Therapy of Gallbladder Cancer

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Gallbladder Cancer

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Abstract

Gallbladder cancer is a rare gastrointestinal malignancy having a poor prognosis because of its late presentation of disease, early invasion, and lack of effective systemic therapy. Surgical extirpation with negative margins remains the only chance for cure in patients with gallbladder cancer. Despite the best attempts at curative resection, a majority of patients with GBC usually recur. Therefore, effective adjuvant therapies are needed to decrease disease recurrence and to improve survival. Recurrence following surgery is a major barrier to providing long-term survival in patients with GBC. The use of adjuvant therapy has been found to be effective through various clinical trials. In the present chapter, we have discussed the data on adjuvant treatment of GBC and explore therapeutic methods for the patients in the adjuvant setting.

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Authors and Affiliations

  1. The Ohio State University Wexner Medical Center, Columbus, OH, USA

    Zachary J. Brown, Daniel B. Hewitt & Timothy M. Pawlik

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  1. Zachary J. Brown
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  2. Daniel B. Hewitt
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  3. Timothy M. Pawlik
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Correspondence to Timothy M. Pawlik .

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Editors and Affiliations

  1. Department of General Surgery, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Vijay Kumar Shukla

  2. Department of Surgical Oncology, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Manoj Pandey

  3. Department of General Surgery, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Ruhi Dixit

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Brown, Z.J., Hewitt, D.B., Pawlik, T.M. (2023). Adjuvant Therapy of Gallbladder Cancer. In: Kumar Shukla, V., Pandey, M., Dixit, R. (eds) Gallbladder Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-19-6442-8_4

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  • DOI: https://doi.org/10.1007/978-981-19-6442-8_4

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