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Molecular Mechanisms of Antimicrobial Resistance

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Handbook on Antimicrobial Resistance

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Abstract

Antibiotics were the biggest discovery in the twentieth century and have positively impacted infection treatment in human and animal health. After several decades of use and misuse of antibiotics, the world is now racing toward pre-antibiotic era with the development of resistance in bacteria to the maximum number of antibiotics. The development and spread of resistance are mediated through several mechanisms evolved due to the immense genetic plasticity of bacteria. Understanding the underlying molecular basis of antimicrobial resistance (AMR) is pertinent to develop new drugs or design appropriate strategies to prevent the emergence of resistance. The present chapter is a ready reckoner for the mode of action of antibiotics, mechanism of AMR, and transfer of its resistance.

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Authors and Affiliations

  1. Microbiology, Fermentation and Biotechnology Division, ICAR-Central Institute of Fisheries Technology (ICAR-CIFT), Cochin, Kerala, India

    Murugadas Vaiyapuri

  2. Research Centre of ICAR-CIFT, Visakhapatnam, Andhra Pradesh, India

    Ahamed Basha Kusunur & Madhusudana Rao Badireddy

Authors
  1. Murugadas Vaiyapuri
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  2. Ahamed Basha Kusunur
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  3. Madhusudana Rao Badireddy
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Corresponding author

Correspondence to Madhusudana Rao Badireddy .

Editor information

Editors and Affiliations

  1. ICAR-Central Institute of Fisheries Tech, Kerala, India

    Mukteswar Prasad Mothadaka

  2. ICAR-Central Institute of Fisheries Tech, Kerala, India

    Murugadas Vaiyapuri

  3. Visakhapatnam Research Centre, ICAR-Central Institute of Fisheries Tech, Visakhapatnam, Andhra Pradesh, India

    Madhusudana Rao Badireddy

  4. ICAR-Central Institute of Fisheries Tech, Kerala, India

    Chandragiri Nagarajrao Ravishankar

  5. World Health Organization Regional Offic, New Delhi, India

    Rajesh Bhatia

  6. Indian Council of Agricultural Research, New Delhi, India

    Joykrushna Jena

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Vaiyapuri, M., Kusunur, A.B., Badireddy, M.R. (2023). Molecular Mechanisms of Antimicrobial Resistance. In: Mothadaka, M.P., Vaiyapuri, M., Rao Badireddy, M., Nagarajrao Ravishankar, C., Bhatia, R., Jena, J. (eds) Handbook on Antimicrobial Resistance. Springer, Singapore. https://doi.org/10.1007/978-981-16-9723-4_28-1

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  • DOI: https://doi.org/10.1007/978-981-16-9723-4_28-1

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  • Print ISBN: 978-981-16-9723-4

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