Abstract
Photodynamic therapy (PDT) is one of the most promising emerging treatment modality for treatment of various types of cancers. Effectiveness of PDT with its lesser side effects and preservation of functions of nearby tissues shows a way to much comforting treatment modality than other treatment options present today. Various studies have demonstrated and confirmed the effective role of PDT in controlling the progression of early stages of lung cancers. And this is achieved by using photosensitizing agents which when present in targeted tumor issues, increase response to light of particular wavelength and destroys the cells at tumor site only. This occurs by role of free radical production in targeted cells, out of which reactive oxygen species have been studied extensively. And the overall positive effect of PDT can be of much use if we can diagnose timely about the staging of lung cancers, then we can achieve better outcome with fewer unwanted negative effects. In fact some countries have already adopted PDT as part of standard treatment of early stages lung cancer along with other modalities. PDT can open up new paths to decrease painful experience for these patients whether it is major surgeries or chemotherapy.
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Kumar, R., Dalal, D., Gupta, K., Dahiya, K. (2022). Photodynamic Therapy and ROS. In: Chakraborti, S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-5422-0_268
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DOI: https://doi.org/10.1007/978-981-16-5422-0_268
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