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Ionically Gelled Gellan Gum in Drug Delivery

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Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery

Part of the book series: Gels Horizons: From Science to Smart Materials ((GHFSSM))

Abstract

Gellan gum (GG) is a bacterial exopolysaccharide obtained commercially from Sphingomonas paucimobilis. Two chemical forms of GG exist, i.e. native/acylated and deacylated. Ionotropic/ionic gelation is a promising tool in the development of biocompatible novel drug delivery systems. GG is a naturally occurring polysaccharide that bears the potential to encapsulate a large number of micro- and macro-therapeutic molecules via different carrier systems such as microspheres, hydrogels, beads and microparticles. By the achievements of polymer chemistry, development of intelligent and the strategic encapsulation techniques helps the natural polysaccharide to use in numerous drug delivery. The usage of expensive and toxic organic solvents in the microencapsulation process has been significantly minimized by the progress of ionotropic gelation method. Ionically gelled GG delivers great prospects for designing new drug delivery systems, thus encompassing the frontier of future pharmaceutical development.

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Author information

Authors and Affiliations

  1. Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, School of Engineering & Techology, Dr. Hari Singh Gour Central University, Sagar, 470003, Madhya Pradesh, India

    Pritish Kumar Panda, Amit Verma, Shivani Saraf, Ankita Tiwari & Sanjay K. Jain

Authors
  1. Pritish Kumar Panda
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  2. Amit Verma
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  3. Shivani Saraf
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  4. Ankita Tiwari
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  5. Sanjay K. Jain
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Editor information

Editors and Affiliations

  1. Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Jharpokharia, Odisha, India

    Amit Kumar Nayak

  2. Department of Pharmacy, Palamau Institute of Pharmacy, Daltonganj, Jharkhand, India

    Md Saquib Hasnain

  3. Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India

    Dilipkumar Pal

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Panda, P.K., Verma, A., Saraf, S., Tiwari, A., Jain, S.K. (2021). Ionically Gelled Gellan Gum in Drug Delivery. In: Nayak, A.K., Hasnain, M.S., Pal, D. (eds) Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery. Gels Horizons: From Science to Smart Materials. Springer, Singapore. https://doi.org/10.1007/978-981-16-2271-7_3

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