Abstract
The glandular morphology analysis done within the colon histopathological images is an imperative step for grade determination of colon cancer. But the manual segmentation is quite laborious as well as time-consuming. It also suffers from the subjectivity among pathologists. Thus, the rising computational pathology has escorted to the development of various automated methods for the gland segmentation task. However, automated gland segmentation remains an exigent task due to numerous factors like the need for high-level resolution for precise delineation of glandular boundaries, etc. Thus, in order to alleviate the development of automated gland segmentation techniques, various image enhancement techniques are applied on colon cancer images for preprocessing them in order to get an enhanced image in which all the critical elements are easily detectable. The enhancement results are analyzed based on both objective qualitative assessment as well as subjective assessment given in the form of scores by the pathologists. And thus based on the qualitative analysis, a new combined technique, i.e., colormap-enhanced image sharpening, is proposed in order to get an enhanced image in which all the critical elements are easily detectable. These techniques’ results will thus help pathologists in better colon histopathology image analysis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Fleming M, Ravula S, Tatishchev SF, Wang HL (2012) Colorectal carcinoma: Pathologic aspects. J Gastrointest Oncol 3(3):153
Gurcan MN, Boucheron L, Can A, Madabhushi A, Rajpoot N, Yener B (2009) Histopathological image analysis: a review. IEEE Rev Biomed Eng 2:147
Gonzalez RC, Woods, Richards E (2018) Image processing. Digit Image Proc Intensity Trans Spatial Filtering
Sirinukunwattana K, Pluim JP, Chen H, Qi X, Heng PA, Guo YB, Wang LY, Matuszewski BJ, Bruni E, Sanchez U, Böhm A (2017) Gland segmentation in colon histology images: the glas challenge contest. Med Image Anal 35:489–502
Warwick-QU image dataset description. https://warwick.ac.uk/fac/sci/dcs/research/tia/glascontest/about/
Jeevakala S (2018) Sharpening enhancement technique for MR images to enhance the segmentation. Biomed Signal Process Control 41:21–30
Reddy E, Reddy R (2018) Dynamic clipped histogram equalization technique for enhancing low contrast images. Proc National Acad Sci India Sect A Phys Sci 1–26
Sahu S, Singh AK, Ghrera SP, Elhoseny M (2019) An approach for de-noising and contrast enhancement of retinal fundus image using CLAHE. Opt Laser Technol 110:87–98
Cao G, Huang L, Tian H, Huang X, Wang Y, Zhi R (2018) Contrast enhancement of brightness-distorted images by improved adaptive gamma correction. Comput Electr Eng 66:569–582
Duan X, Mei Y, Wu S, Ling Q, Qin G, Ma J, Chen C, Qi H, Zhou L, Xu Y (2018) A multiscale contrast enhancement for mammogram using dynamic unsharp masking in Laplacian pyramid. In: IEEE transactions on radiation and plasma medical sciences
Hsu WY, Chou CY (2015) Medical image enhancement using modified color histogram equalization. J Med Biol Eng 35(5):580–584
Li L, Si Y, Jia Z (2018) Medical image enhancement based on CLAHE and unsharp masking in NSCT domain. J Med Imaging Health Inf 8(3):431–438
Ullah Z, Lee SH (2019) Magnetic resonance brain image contrast enhancement using histogram equalization techniques. 한국컴퓨터정보학회 학술발표논문집 27(1):83–86
Mzoughi H, Njeh I, Slima MB, Hamida AB (2018) Histogram equalization-based techniques for contrast enhancement of MRI brain Glioma tumor images: Comparative study. In: 2018 4th International conference on advanced technologies for signal and image processing (ATSIP), pp. 1–6. IEEE
Dhal KG, Das S (2018) Colour retinal images enhancement using modified histogram equalisation methods and firefly algorithm. Int J Biomed Eng Technol 28(2):160–184
Clark JL, Wadhwani CP, Abramovitch K, Rice DD, Kattadiyil MT (2018) Effect of image sharpening on radiographic image quality. J Prosthet Dent 120(6):927–933
Tiwari M, Gupta B (2016) Brightness preserving contrast enhancement of medical images using adaptive gamma correction and homomorphic filtering. In: 2016 IEEE Students’ conference on electrical, electronics and computer science (SCEECS), pp 1–4. IEEE
Bhairannawar SS (2018) Efficient medical image enhancement technique using transform HSV space and adaptive histogram equalization. In: Soft computing based medical image analysis academic press, pp 51–60
Dabass J, Arora S, Vig R, Hanmandlu M (2019) Mammogram image enhancement using entropy and CLAHE based intuitionistic fuzzy method. In: 2019 6th International conference on signal processing and integrated networks (SPIN), IEEE, pp 24–29
Dabass M, Vashisth S, Vig R (2019) Review of classification techniques using deep learning for colorectal cancer imaging modalities. In: 2019 6th International conference on signal processing and integrated networks (SPIN) IEEE, pp 105–110
Dabass M, Vig R, Vashisth S (2018) Five-grade cancer classification of colon histology images via deep learning. In: 2018 2nd international conference on commuincation and computing system (ICCCS), Taylor and Francis
Dabass M, Vig R, Vashisth S (2018) Review of histopathological image segmentation via current deep learning approaches. In: 2019 4th IEEE international conference on computing communication and automation (ICCCA)
Acknowledgements
The authors are grateful to Dr. Hema Malini Aiyer, Head of Pathology, and Dr. Garima Rawat, Pathologist at Dharamshila Narayana Superspeciality Hospital, New Delhi, for their support to our research, and without their help, we will not be able to check the feasibility of the applied algorithm in the real-life scenario.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Dabass, M., Dabass, J. (2021). Preprocessing Techniques for Colon Histopathology Images. In: Hura, G.S., Singh, A.K., Siong Hoe, L. (eds) Advances in Communication and Computational Technology. ICACCT 2019. Lecture Notes in Electrical Engineering, vol 668. Springer, Singapore. https://doi.org/10.1007/978-981-15-5341-7_85
Download citation
DOI: https://doi.org/10.1007/978-981-15-5341-7_85
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-5340-0
Online ISBN: 978-981-15-5341-7
eBook Packages: EngineeringEngineering (R0)