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Gastrointestinal Involvement of Systemic Vasculitis

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Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases

Abstract

Systemic vasculitides can affect any organ and any part of the gastrointestinal tract, including the hepatobiliary system. Depending on the size of the inflamed blood vessels, gastrointestinal symptoms may range from mild abdominal pain and elevated transaminase levels to potentially life-threatening intestinal perforations and peritonitis. Because gastrointestinal manifestations are not specific, a diagnosis of systemic vasculitis based on gastrointestinal symptoms alone is challenging. However, diagnostic delay can cause unfavorable outcomes. This article reviews the epidemiology, gastrointestinal manifestations, and treatment of systemic vasculitides including Takayasu arteritis, polyarteritis nodosa, antineutrophil cytoplasm antibody-associated vasculitis, and single-organ vasculitis limited to the gastrointestinal tract.

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Acknowledgment

We thank Katrina Krogh, M.D., from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.

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Authors and Affiliations

  1. Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan

    Shuzo Sato & Kiyoshi Migita

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  1. Shuzo Sato
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  2. Kiyoshi Migita
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Correspondence to Shuzo Sato .

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Editors and Affiliations

  1. Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan

    Hiromasa Ohira

  2. Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan

    Kiyoshi Migita

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Sato, S., Migita, K. (2019). Gastrointestinal Involvement of Systemic Vasculitis. In: Ohira, H., Migita, K. (eds) Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-13-6524-9_9

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  • DOI: https://doi.org/10.1007/978-981-13-6524-9_9

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